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Design of 3D-Printed Electronic Fiber Optic Sensor to Detect Rhodamine B Reagent: An Initiation to Potential Virus Detection

A fluorescence device based on ultraviolet light is proposed in this paper, which currently stands at the design stage with the eventual aim to potentially detect virus/antibody fluorescence reactions. The designed device is proposed to have the characteristics of high reflectivity, low power consum...

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Detalles Bibliográficos
Autores principales: Guo, Ningyuan, Liu, Jingwen, He, Qing, Zhou, Rongyan, Yuan, Haobo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9326570/
https://www.ncbi.nlm.nih.gov/pubmed/35892364
http://dx.doi.org/10.3390/biomimetics7030094
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author Guo, Ningyuan
Liu, Jingwen
He, Qing
Zhou, Rongyan
Yuan, Haobo
author_facet Guo, Ningyuan
Liu, Jingwen
He, Qing
Zhou, Rongyan
Yuan, Haobo
author_sort Guo, Ningyuan
collection PubMed
description A fluorescence device based on ultraviolet light is proposed in this paper, which currently stands at the design stage with the eventual aim to potentially detect virus/antibody fluorescence reactions. The designed device is proposed to have the characteristics of high reflectivity, low power consumption, wide spectrum of light source, and proper silver coating. For fabrication and raising product quality, 3D printing technology and a sputtering test will be used. In this connection, this paper firstly introduces the design sources; then, the ideas of inventing fluorescence detection devices based on ultraviolet light, followed by the data analysis as well as discussing the results of computer simulations. The design process, materials, methods, and experiments are demonstrated following the reality work procedure. Instead of directly using a virus or antibodies for the experiment, at the current design stage, we focus on using this device to detect the rhodamine B reagent. Experiment shows that this reagent can be successfully detected. With this achievement, we logically believe that such type of an ultraviolet optical sensor, with further development and testing, may have the possible value to detect a single virus such as COVID-19, as well as other viruses or small molecules. Though there is long way to go to achieve such a goal, future works experimenting with the detection device on real virus or antibodies can take place more efficiently with a good foundation.
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spelling pubmed-93265702022-07-28 Design of 3D-Printed Electronic Fiber Optic Sensor to Detect Rhodamine B Reagent: An Initiation to Potential Virus Detection Guo, Ningyuan Liu, Jingwen He, Qing Zhou, Rongyan Yuan, Haobo Biomimetics (Basel) Article A fluorescence device based on ultraviolet light is proposed in this paper, which currently stands at the design stage with the eventual aim to potentially detect virus/antibody fluorescence reactions. The designed device is proposed to have the characteristics of high reflectivity, low power consumption, wide spectrum of light source, and proper silver coating. For fabrication and raising product quality, 3D printing technology and a sputtering test will be used. In this connection, this paper firstly introduces the design sources; then, the ideas of inventing fluorescence detection devices based on ultraviolet light, followed by the data analysis as well as discussing the results of computer simulations. The design process, materials, methods, and experiments are demonstrated following the reality work procedure. Instead of directly using a virus or antibodies for the experiment, at the current design stage, we focus on using this device to detect the rhodamine B reagent. Experiment shows that this reagent can be successfully detected. With this achievement, we logically believe that such type of an ultraviolet optical sensor, with further development and testing, may have the possible value to detect a single virus such as COVID-19, as well as other viruses or small molecules. Though there is long way to go to achieve such a goal, future works experimenting with the detection device on real virus or antibodies can take place more efficiently with a good foundation. MDPI 2022-07-09 /pmc/articles/PMC9326570/ /pubmed/35892364 http://dx.doi.org/10.3390/biomimetics7030094 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Guo, Ningyuan
Liu, Jingwen
He, Qing
Zhou, Rongyan
Yuan, Haobo
Design of 3D-Printed Electronic Fiber Optic Sensor to Detect Rhodamine B Reagent: An Initiation to Potential Virus Detection
title Design of 3D-Printed Electronic Fiber Optic Sensor to Detect Rhodamine B Reagent: An Initiation to Potential Virus Detection
title_full Design of 3D-Printed Electronic Fiber Optic Sensor to Detect Rhodamine B Reagent: An Initiation to Potential Virus Detection
title_fullStr Design of 3D-Printed Electronic Fiber Optic Sensor to Detect Rhodamine B Reagent: An Initiation to Potential Virus Detection
title_full_unstemmed Design of 3D-Printed Electronic Fiber Optic Sensor to Detect Rhodamine B Reagent: An Initiation to Potential Virus Detection
title_short Design of 3D-Printed Electronic Fiber Optic Sensor to Detect Rhodamine B Reagent: An Initiation to Potential Virus Detection
title_sort design of 3d-printed electronic fiber optic sensor to detect rhodamine b reagent: an initiation to potential virus detection
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9326570/
https://www.ncbi.nlm.nih.gov/pubmed/35892364
http://dx.doi.org/10.3390/biomimetics7030094
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