DSIF modulates RNA polymerase II occupancy according to template G + C content

The DSIF complex comprising the Supt4h and Supt5h transcription elongation proteins clamps RNA polymerase II (RNAPII) onto DNA templates, facilitating polymerase processivity. Lowering DSIF components can differentially decrease expression of alleles containing nucleotide repeat expansions, suggesti...

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Detalles Bibliográficos
Autores principales: Deng, Ning, Zhang, Yue, Ma, Zhihai, Lin, Richard, Cheng, Tzu-Hao, Tang, Hua, Snyder, Michael P, Cohen, Stanley N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Standard Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9326580/
https://www.ncbi.nlm.nih.gov/pubmed/35910045
http://dx.doi.org/10.1093/nargab/lqac054

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9326580/
https://www.ncbi.nlm.nih.gov/pubmed/35910045
http://dx.doi.org/10.1093/nargab/lqac054

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