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DSIF modulates RNA polymerase II occupancy according to template G + C content
The DSIF complex comprising the Supt4h and Supt5h transcription elongation proteins clamps RNA polymerase II (RNAPII) onto DNA templates, facilitating polymerase processivity. Lowering DSIF components can differentially decrease expression of alleles containing nucleotide repeat expansions, suggesti...
Autores principales: | Deng, Ning, Zhang, Yue, Ma, Zhihai, Lin, Richard, Cheng, Tzu-Hao, Tang, Hua, Snyder, Michael P, Cohen, Stanley N |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9326580/ https://www.ncbi.nlm.nih.gov/pubmed/35910045 http://dx.doi.org/10.1093/nargab/lqac054 |
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