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Secondary Complications in COVID-19 Patients: A Case Series

Introduction. Coronavirus SARS-CoV-2, the causative agent of COVID-19, primarily causes a respiratory tract infection that is not limited to respiratory distress syndrome, but it is also implicated in other body systems. Systemic complications were reported due to an exaggerated inflammatory respons...

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Autores principales: Belfiore, Maria Paola, Russo, Gaetano Maria, Gallo, Luigi, Atripaldi, Umberto, Tamburrini, Stefania, Caliendo, Valentina, Impieri, Luigi, Del Canto, Maria Teresa, Ciani, Giovanni, Parrella, Pasquale, Mangoni di Santo Stefano, Maria Luisa, Salvia, Antonio Alessandro Heliot, Urraro, Fabrizio, Nardone, Valerio, Coppola, Nicola, Reginelli, Alfonso, Cappabianca, Salvatore
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9326591/
https://www.ncbi.nlm.nih.gov/pubmed/35894019
http://dx.doi.org/10.3390/tomography8040154
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author Belfiore, Maria Paola
Russo, Gaetano Maria
Gallo, Luigi
Atripaldi, Umberto
Tamburrini, Stefania
Caliendo, Valentina
Impieri, Luigi
Del Canto, Maria Teresa
Ciani, Giovanni
Parrella, Pasquale
Mangoni di Santo Stefano, Maria Luisa
Salvia, Antonio Alessandro Heliot
Urraro, Fabrizio
Nardone, Valerio
Coppola, Nicola
Reginelli, Alfonso
Cappabianca, Salvatore
author_facet Belfiore, Maria Paola
Russo, Gaetano Maria
Gallo, Luigi
Atripaldi, Umberto
Tamburrini, Stefania
Caliendo, Valentina
Impieri, Luigi
Del Canto, Maria Teresa
Ciani, Giovanni
Parrella, Pasquale
Mangoni di Santo Stefano, Maria Luisa
Salvia, Antonio Alessandro Heliot
Urraro, Fabrizio
Nardone, Valerio
Coppola, Nicola
Reginelli, Alfonso
Cappabianca, Salvatore
author_sort Belfiore, Maria Paola
collection PubMed
description Introduction. Coronavirus SARS-CoV-2, the causative agent of COVID-19, primarily causes a respiratory tract infection that is not limited to respiratory distress syndrome, but it is also implicated in other body systems. Systemic complications were reported due to an exaggerated inflammatory response, which involves severe alveolar damage in the lungs and exacerbates the hypercoagulation that leads to venous thrombosis, ischemic attack, vascular dysfunction and infarction of visceral abdominal organs. Some complications are related to anticoagulant drugs that are administrated to stabilize hypercoagulability, but increase the risk of bleeding, hematoma and hemorrhage. The aim of this study is to report the diagnostic role of CT in the early diagnosis and management of patients with severe COVID-19 complications through the most interesting cases in our experience. Material and Methods. The retrospective analysis of patients studied for COVID-19 in our institution and hospitals, which are part of the university training network, was performed. Cases. Pneumomediastinum, cortical kidney necrosis, splenic infarction, cerebral ischemic stroke, thrombosis of the lower limb and hematomas are the most major complications that are reviewed in this study. Conclusions. Since the onset of the COVID-19 pandemic, the CT imaging modality with its high sensitivity and specificity remains the preferred imaging choice to diagnose early the different complications associated with COVID-19, such as thrombosis, ischemic stroke, infarction and pneumomediastinum, and their management, which significantly improved the outcomes.
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spelling pubmed-93265912022-07-28 Secondary Complications in COVID-19 Patients: A Case Series Belfiore, Maria Paola Russo, Gaetano Maria Gallo, Luigi Atripaldi, Umberto Tamburrini, Stefania Caliendo, Valentina Impieri, Luigi Del Canto, Maria Teresa Ciani, Giovanni Parrella, Pasquale Mangoni di Santo Stefano, Maria Luisa Salvia, Antonio Alessandro Heliot Urraro, Fabrizio Nardone, Valerio Coppola, Nicola Reginelli, Alfonso Cappabianca, Salvatore Tomography Case Report Introduction. Coronavirus SARS-CoV-2, the causative agent of COVID-19, primarily causes a respiratory tract infection that is not limited to respiratory distress syndrome, but it is also implicated in other body systems. Systemic complications were reported due to an exaggerated inflammatory response, which involves severe alveolar damage in the lungs and exacerbates the hypercoagulation that leads to venous thrombosis, ischemic attack, vascular dysfunction and infarction of visceral abdominal organs. Some complications are related to anticoagulant drugs that are administrated to stabilize hypercoagulability, but increase the risk of bleeding, hematoma and hemorrhage. The aim of this study is to report the diagnostic role of CT in the early diagnosis and management of patients with severe COVID-19 complications through the most interesting cases in our experience. Material and Methods. The retrospective analysis of patients studied for COVID-19 in our institution and hospitals, which are part of the university training network, was performed. Cases. Pneumomediastinum, cortical kidney necrosis, splenic infarction, cerebral ischemic stroke, thrombosis of the lower limb and hematomas are the most major complications that are reviewed in this study. Conclusions. Since the onset of the COVID-19 pandemic, the CT imaging modality with its high sensitivity and specificity remains the preferred imaging choice to diagnose early the different complications associated with COVID-19, such as thrombosis, ischemic stroke, infarction and pneumomediastinum, and their management, which significantly improved the outcomes. MDPI 2022-07-15 /pmc/articles/PMC9326591/ /pubmed/35894019 http://dx.doi.org/10.3390/tomography8040154 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Belfiore, Maria Paola
Russo, Gaetano Maria
Gallo, Luigi
Atripaldi, Umberto
Tamburrini, Stefania
Caliendo, Valentina
Impieri, Luigi
Del Canto, Maria Teresa
Ciani, Giovanni
Parrella, Pasquale
Mangoni di Santo Stefano, Maria Luisa
Salvia, Antonio Alessandro Heliot
Urraro, Fabrizio
Nardone, Valerio
Coppola, Nicola
Reginelli, Alfonso
Cappabianca, Salvatore
Secondary Complications in COVID-19 Patients: A Case Series
title Secondary Complications in COVID-19 Patients: A Case Series
title_full Secondary Complications in COVID-19 Patients: A Case Series
title_fullStr Secondary Complications in COVID-19 Patients: A Case Series
title_full_unstemmed Secondary Complications in COVID-19 Patients: A Case Series
title_short Secondary Complications in COVID-19 Patients: A Case Series
title_sort secondary complications in covid-19 patients: a case series
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9326591/
https://www.ncbi.nlm.nih.gov/pubmed/35894019
http://dx.doi.org/10.3390/tomography8040154
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