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Urinary Transthyretin as a Biomarker in ATTRv Val50Met Amyloidosis

Transthyretin (TTR), the precursor protein for amyloidogenic TTR (ATTR) amyloidosis, forms tetramers and escapes glomerular filtration by binding with thyroxine and retinol-binding protein. However, variant TTRs are unstable as tetramers, so monomeric TTR has become the precursor protein of amyloid...

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Detalles Bibliográficos
Autores principales: Matsushita, Hiroaki, Misumi, Yohei, Masuda, Teruaki, Okada, Masamitsu, Inoue, Fumika, Ueda, Mitsuharu, Ando, Yukio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9326616/
https://www.ncbi.nlm.nih.gov/pubmed/35893595
http://dx.doi.org/10.3390/pathophysiology29030025