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Neurocysticercosis in Low- and Middle-Income Countries, a Diagnostic Challenge from Oyam District, Uganda

Background: In countries where Taenia solium is endemic, neurocysticercosis (NCC) is the leading identified cause of seizures, accounting for nearly 30% of all epilepsy cases and up to 2.8 million of Disability Adjusted Life Years. Diagnosis of this condition, however, is strictly reliant on either...

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Autores principales: Segala, Francesco Vladimiro, De Vita, Elda, Amone, James, Ongaro, Daniel, Nassali, Ritah, Oceng, Bonny, Okori, Samuel, Putoto, Giovanni, Lochoro, Peter, Ictho, Jerry, Fantoni, Massimo, Saracino, Annalisa, Di Gennaro, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9326654/
https://www.ncbi.nlm.nih.gov/pubmed/35893473
http://dx.doi.org/10.3390/idr14040054
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author Segala, Francesco Vladimiro
De Vita, Elda
Amone, James
Ongaro, Daniel
Nassali, Ritah
Oceng, Bonny
Okori, Samuel
Putoto, Giovanni
Lochoro, Peter
Ictho, Jerry
Fantoni, Massimo
Saracino, Annalisa
Di Gennaro, Francesco
author_facet Segala, Francesco Vladimiro
De Vita, Elda
Amone, James
Ongaro, Daniel
Nassali, Ritah
Oceng, Bonny
Okori, Samuel
Putoto, Giovanni
Lochoro, Peter
Ictho, Jerry
Fantoni, Massimo
Saracino, Annalisa
Di Gennaro, Francesco
author_sort Segala, Francesco Vladimiro
collection PubMed
description Background: In countries where Taenia solium is endemic, neurocysticercosis (NCC) is the leading identified cause of seizures, accounting for nearly 30% of all epilepsy cases and up to 2.8 million of Disability Adjusted Life Years. Diagnosis of this condition, however, is strictly reliant on either MRI or CT scan, which are poorly available in low- and middle-income countries (LMICs), creating challenges for proper case management and the acquisition of precise neuroepidemiologic data that may guide program and policy development. Methods: Here, we report the case of a 73-year-old woman admitted in a rural hospital in Northern Uganda, who presented with seizures and a progressive inability to walk. She was then diagnosed with NCC after a brain CT scan. Conclusions: This case study represents a rare example of the detection of NCC in a rural district hospital, thus suggesting the potential feasibility of a CT-scan guided diagnostic approach in low resource settings.
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spelling pubmed-93266542022-07-28 Neurocysticercosis in Low- and Middle-Income Countries, a Diagnostic Challenge from Oyam District, Uganda Segala, Francesco Vladimiro De Vita, Elda Amone, James Ongaro, Daniel Nassali, Ritah Oceng, Bonny Okori, Samuel Putoto, Giovanni Lochoro, Peter Ictho, Jerry Fantoni, Massimo Saracino, Annalisa Di Gennaro, Francesco Infect Dis Rep Case Report Background: In countries where Taenia solium is endemic, neurocysticercosis (NCC) is the leading identified cause of seizures, accounting for nearly 30% of all epilepsy cases and up to 2.8 million of Disability Adjusted Life Years. Diagnosis of this condition, however, is strictly reliant on either MRI or CT scan, which are poorly available in low- and middle-income countries (LMICs), creating challenges for proper case management and the acquisition of precise neuroepidemiologic data that may guide program and policy development. Methods: Here, we report the case of a 73-year-old woman admitted in a rural hospital in Northern Uganda, who presented with seizures and a progressive inability to walk. She was then diagnosed with NCC after a brain CT scan. Conclusions: This case study represents a rare example of the detection of NCC in a rural district hospital, thus suggesting the potential feasibility of a CT-scan guided diagnostic approach in low resource settings. MDPI 2022-07-01 /pmc/articles/PMC9326654/ /pubmed/35893473 http://dx.doi.org/10.3390/idr14040054 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Segala, Francesco Vladimiro
De Vita, Elda
Amone, James
Ongaro, Daniel
Nassali, Ritah
Oceng, Bonny
Okori, Samuel
Putoto, Giovanni
Lochoro, Peter
Ictho, Jerry
Fantoni, Massimo
Saracino, Annalisa
Di Gennaro, Francesco
Neurocysticercosis in Low- and Middle-Income Countries, a Diagnostic Challenge from Oyam District, Uganda
title Neurocysticercosis in Low- and Middle-Income Countries, a Diagnostic Challenge from Oyam District, Uganda
title_full Neurocysticercosis in Low- and Middle-Income Countries, a Diagnostic Challenge from Oyam District, Uganda
title_fullStr Neurocysticercosis in Low- and Middle-Income Countries, a Diagnostic Challenge from Oyam District, Uganda
title_full_unstemmed Neurocysticercosis in Low- and Middle-Income Countries, a Diagnostic Challenge from Oyam District, Uganda
title_short Neurocysticercosis in Low- and Middle-Income Countries, a Diagnostic Challenge from Oyam District, Uganda
title_sort neurocysticercosis in low- and middle-income countries, a diagnostic challenge from oyam district, uganda
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9326654/
https://www.ncbi.nlm.nih.gov/pubmed/35893473
http://dx.doi.org/10.3390/idr14040054
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