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Neurocysticercosis in Low- and Middle-Income Countries, a Diagnostic Challenge from Oyam District, Uganda
Background: In countries where Taenia solium is endemic, neurocysticercosis (NCC) is the leading identified cause of seizures, accounting for nearly 30% of all epilepsy cases and up to 2.8 million of Disability Adjusted Life Years. Diagnosis of this condition, however, is strictly reliant on either...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9326654/ https://www.ncbi.nlm.nih.gov/pubmed/35893473 http://dx.doi.org/10.3390/idr14040054 |
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author | Segala, Francesco Vladimiro De Vita, Elda Amone, James Ongaro, Daniel Nassali, Ritah Oceng, Bonny Okori, Samuel Putoto, Giovanni Lochoro, Peter Ictho, Jerry Fantoni, Massimo Saracino, Annalisa Di Gennaro, Francesco |
author_facet | Segala, Francesco Vladimiro De Vita, Elda Amone, James Ongaro, Daniel Nassali, Ritah Oceng, Bonny Okori, Samuel Putoto, Giovanni Lochoro, Peter Ictho, Jerry Fantoni, Massimo Saracino, Annalisa Di Gennaro, Francesco |
author_sort | Segala, Francesco Vladimiro |
collection | PubMed |
description | Background: In countries where Taenia solium is endemic, neurocysticercosis (NCC) is the leading identified cause of seizures, accounting for nearly 30% of all epilepsy cases and up to 2.8 million of Disability Adjusted Life Years. Diagnosis of this condition, however, is strictly reliant on either MRI or CT scan, which are poorly available in low- and middle-income countries (LMICs), creating challenges for proper case management and the acquisition of precise neuroepidemiologic data that may guide program and policy development. Methods: Here, we report the case of a 73-year-old woman admitted in a rural hospital in Northern Uganda, who presented with seizures and a progressive inability to walk. She was then diagnosed with NCC after a brain CT scan. Conclusions: This case study represents a rare example of the detection of NCC in a rural district hospital, thus suggesting the potential feasibility of a CT-scan guided diagnostic approach in low resource settings. |
format | Online Article Text |
id | pubmed-9326654 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-93266542022-07-28 Neurocysticercosis in Low- and Middle-Income Countries, a Diagnostic Challenge from Oyam District, Uganda Segala, Francesco Vladimiro De Vita, Elda Amone, James Ongaro, Daniel Nassali, Ritah Oceng, Bonny Okori, Samuel Putoto, Giovanni Lochoro, Peter Ictho, Jerry Fantoni, Massimo Saracino, Annalisa Di Gennaro, Francesco Infect Dis Rep Case Report Background: In countries where Taenia solium is endemic, neurocysticercosis (NCC) is the leading identified cause of seizures, accounting for nearly 30% of all epilepsy cases and up to 2.8 million of Disability Adjusted Life Years. Diagnosis of this condition, however, is strictly reliant on either MRI or CT scan, which are poorly available in low- and middle-income countries (LMICs), creating challenges for proper case management and the acquisition of precise neuroepidemiologic data that may guide program and policy development. Methods: Here, we report the case of a 73-year-old woman admitted in a rural hospital in Northern Uganda, who presented with seizures and a progressive inability to walk. She was then diagnosed with NCC after a brain CT scan. Conclusions: This case study represents a rare example of the detection of NCC in a rural district hospital, thus suggesting the potential feasibility of a CT-scan guided diagnostic approach in low resource settings. MDPI 2022-07-01 /pmc/articles/PMC9326654/ /pubmed/35893473 http://dx.doi.org/10.3390/idr14040054 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Case Report Segala, Francesco Vladimiro De Vita, Elda Amone, James Ongaro, Daniel Nassali, Ritah Oceng, Bonny Okori, Samuel Putoto, Giovanni Lochoro, Peter Ictho, Jerry Fantoni, Massimo Saracino, Annalisa Di Gennaro, Francesco Neurocysticercosis in Low- and Middle-Income Countries, a Diagnostic Challenge from Oyam District, Uganda |
title | Neurocysticercosis in Low- and Middle-Income Countries, a Diagnostic Challenge from Oyam District, Uganda |
title_full | Neurocysticercosis in Low- and Middle-Income Countries, a Diagnostic Challenge from Oyam District, Uganda |
title_fullStr | Neurocysticercosis in Low- and Middle-Income Countries, a Diagnostic Challenge from Oyam District, Uganda |
title_full_unstemmed | Neurocysticercosis in Low- and Middle-Income Countries, a Diagnostic Challenge from Oyam District, Uganda |
title_short | Neurocysticercosis in Low- and Middle-Income Countries, a Diagnostic Challenge from Oyam District, Uganda |
title_sort | neurocysticercosis in low- and middle-income countries, a diagnostic challenge from oyam district, uganda |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9326654/ https://www.ncbi.nlm.nih.gov/pubmed/35893473 http://dx.doi.org/10.3390/idr14040054 |
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