Excipient-drug pharmacokinetic interactions: Effect of disintegrants on efflux across excised pig intestinal tissues

Pharmaceutical excipients were designed originally to be pharmacologically inert. However, certain excipients were found to have altering effects on drug pharmacodynamics and/or pharmacokinetics. Pharmacokinetic interactions may be caused by modulation of efflux transporter proteins, intercellular t...

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Detalles Bibliográficos
Autores principales: Gerber, Werner, Hamman, Josias H., Steyn, Johan D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taiwan Food and Drug Administration 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9326877/
https://www.ncbi.nlm.nih.gov/pubmed/29703379
http://dx.doi.org/10.1016/j.jfda.2018.01.007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9326877/
https://www.ncbi.nlm.nih.gov/pubmed/29703379
http://dx.doi.org/10.1016/j.jfda.2018.01.007

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