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Excipient-drug pharmacokinetic interactions: Effect of disintegrants on efflux across excised pig intestinal tissues
Pharmaceutical excipients were designed originally to be pharmacologically inert. However, certain excipients were found to have altering effects on drug pharmacodynamics and/or pharmacokinetics. Pharmacokinetic interactions may be caused by modulation of efflux transporter proteins, intercellular t...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taiwan Food and Drug Administration
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9326877/ https://www.ncbi.nlm.nih.gov/pubmed/29703379 http://dx.doi.org/10.1016/j.jfda.2018.01.007 |