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Immuno-antibiotics: targeting microbial metabolic pathways sensed by unconventional T cells

Human Vγ9/Vδ2 T cells, mucosal-associated invariant T (MAIT) cells, and other unconventional T cells are specialised in detecting microbial metabolic pathway intermediates that are absent in humans. The recognition by such semi-invariant innate-like T cells of compounds like (E)-4-hydroxy-3-methyl-b...

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Detalles Bibliográficos
Autores principales: Eberl, Matthias, Oldfield, Eric, Herrmann, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9327107/
https://www.ncbi.nlm.nih.gov/pubmed/35919736
http://dx.doi.org/10.1093/immadv/ltab005

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