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Safety of the use of gold nanoparticles conjugated with proinsulin peptide and administered by hollow microneedles as an immunotherapy in type 1 diabetes
Antigen-specific immunotherapy is an immunomodulatory strategy for autoimmune diseases, such as type 1 diabetes, in which patients are treated with autoantigens to promote immune tolerance, stop autoimmune β-cell destruction and prevent permanent dependence on exogenous insulin. In this study, human...
Autores principales: | Tatovic, D, McAteer, M A, Barry, J, Barrientos, A, Rodríguez Terradillos, K, Perera, I, Kochba, E, Levin, Y, Dul, M, Coulman, S A, Birchall, J C, von Ruhland, C, Howell, A, Stenson, R, Alhadj Ali, M, Luzio, S D, Dunseath, G, Cheung, W Y, Holland, G, May, K, Ingram, J R, Chowdhury, M M U, Wong, F S, Casas, R, Dayan, C, Ludvigsson, J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9327128/ https://www.ncbi.nlm.nih.gov/pubmed/35919496 http://dx.doi.org/10.1093/immadv/ltac002 |
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