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Hemangiopericytoma/solitary fibrous tumor of the cranial base: a case series and literature review

BACKGROUND: Hemangiopericytomas (HPCs) are uncommon soft tissue tumors. HPCs that grow in the cranial base are rare. Therefore, skull-base surgeons tend to overlook this disease. This study aimed to increase the awareness of HPCs by summarizing case data from our institution and related publications...

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Autores principales: Peng, Zhouying, Wang, Yumin, Wang, Yaxuan, Li, Qinxuan, Fang, Yan, Fan, Ruohao, Zhang, Hua, Jiang, Weihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9327149/
https://www.ncbi.nlm.nih.gov/pubmed/35897071
http://dx.doi.org/10.1186/s12893-022-01718-5
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author Peng, Zhouying
Wang, Yumin
Wang, Yaxuan
Li, Qinxuan
Fang, Yan
Fan, Ruohao
Zhang, Hua
Jiang, Weihong
author_facet Peng, Zhouying
Wang, Yumin
Wang, Yaxuan
Li, Qinxuan
Fang, Yan
Fan, Ruohao
Zhang, Hua
Jiang, Weihong
author_sort Peng, Zhouying
collection PubMed
description BACKGROUND: Hemangiopericytomas (HPCs) are uncommon soft tissue tumors. HPCs that grow in the cranial base are rare. Therefore, skull-base surgeons tend to overlook this disease. This study aimed to increase the awareness of HPCs by summarizing case data from our institution and related publications. We also aimed to contribute to the number of reported cases for future systematic reviews of HPCs. METHODS: This study included all patients who underwent surgery for HPC/solitary fibrous tumor (SFT) between August 2015 and August 2019. All surgeries were performed at Xiangya Hospital Central South University. We analyzed clinical characteristics, surgical highlights, treatment modalities, and outcomes. RESULTS: We included six patients, aged 32–64 years. Lesions were located in the parapharyngeal space in three patients, pterygopalatine fossa in two, and saddle area in one. All patients underwent nasal endoscopic endonasal surgery. In five patients, tumors involved the internal carotid artery (ICA). The exposure and protection of the ICA during surgery are challenging but critical to complete tumor removal. The 3-year overall survival(OS) rate was 66.7%. CONCLUSIONS: HPC/SFTs are rare tumors of the cranial base that are prone to recurrence. Cranial base HPC/SFTs are often closely associated with the ICA. To our knowledge, this case series reports the largest number of cases of HPCs associated with the ICA. We believe that there is a strong relationship between patient prognosis and whether the tumor encircles the ICA and whether the tumor is completely resected. To confirm this suggestion, more cases are needed for further analysis. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12893-022-01718-5.
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spelling pubmed-93271492022-07-28 Hemangiopericytoma/solitary fibrous tumor of the cranial base: a case series and literature review Peng, Zhouying Wang, Yumin Wang, Yaxuan Li, Qinxuan Fang, Yan Fan, Ruohao Zhang, Hua Jiang, Weihong BMC Surg Research BACKGROUND: Hemangiopericytomas (HPCs) are uncommon soft tissue tumors. HPCs that grow in the cranial base are rare. Therefore, skull-base surgeons tend to overlook this disease. This study aimed to increase the awareness of HPCs by summarizing case data from our institution and related publications. We also aimed to contribute to the number of reported cases for future systematic reviews of HPCs. METHODS: This study included all patients who underwent surgery for HPC/solitary fibrous tumor (SFT) between August 2015 and August 2019. All surgeries were performed at Xiangya Hospital Central South University. We analyzed clinical characteristics, surgical highlights, treatment modalities, and outcomes. RESULTS: We included six patients, aged 32–64 years. Lesions were located in the parapharyngeal space in three patients, pterygopalatine fossa in two, and saddle area in one. All patients underwent nasal endoscopic endonasal surgery. In five patients, tumors involved the internal carotid artery (ICA). The exposure and protection of the ICA during surgery are challenging but critical to complete tumor removal. The 3-year overall survival(OS) rate was 66.7%. CONCLUSIONS: HPC/SFTs are rare tumors of the cranial base that are prone to recurrence. Cranial base HPC/SFTs are often closely associated with the ICA. To our knowledge, this case series reports the largest number of cases of HPCs associated with the ICA. We believe that there is a strong relationship between patient prognosis and whether the tumor encircles the ICA and whether the tumor is completely resected. To confirm this suggestion, more cases are needed for further analysis. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12893-022-01718-5. BioMed Central 2022-07-27 /pmc/articles/PMC9327149/ /pubmed/35897071 http://dx.doi.org/10.1186/s12893-022-01718-5 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Peng, Zhouying
Wang, Yumin
Wang, Yaxuan
Li, Qinxuan
Fang, Yan
Fan, Ruohao
Zhang, Hua
Jiang, Weihong
Hemangiopericytoma/solitary fibrous tumor of the cranial base: a case series and literature review
title Hemangiopericytoma/solitary fibrous tumor of the cranial base: a case series and literature review
title_full Hemangiopericytoma/solitary fibrous tumor of the cranial base: a case series and literature review
title_fullStr Hemangiopericytoma/solitary fibrous tumor of the cranial base: a case series and literature review
title_full_unstemmed Hemangiopericytoma/solitary fibrous tumor of the cranial base: a case series and literature review
title_short Hemangiopericytoma/solitary fibrous tumor of the cranial base: a case series and literature review
title_sort hemangiopericytoma/solitary fibrous tumor of the cranial base: a case series and literature review
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9327149/
https://www.ncbi.nlm.nih.gov/pubmed/35897071
http://dx.doi.org/10.1186/s12893-022-01718-5
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