Pretreatment of nucleus pulposus mesenchymal stem cells with appropriate concentration of H(2)O(2) enhances their ability to treat intervertebral disc degeneration

BACKGROUND: Nucleus pulposus mesenchymal stem cells (NPMSCs) transplantation is a promising treatment for intervertebral disc degeneration (IVDD). However, the transplanted NPMSCs exhibited weak cell proliferation, high cell apoptosis, and a low ability to resist the harsh microenvironment of the de...

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Detalles Bibliográficos
Autores principales: Zhang, Yu-yao, Hu, Zhi-lei, Qi, Yu-han, Li, Hai-yin, Chang, Xian, Gao, Xiao-xin, Liu, Chen-hao, Li, Yue-yang, Lou, Jin-hui, Zhai, Yu, Li, Chang-qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9327256/
https://www.ncbi.nlm.nih.gov/pubmed/35883157
http://dx.doi.org/10.1186/s13287-022-03031-7

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