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Exosomal miR-17-5p from adipose-derived mesenchymal stem cells inhibits abdominal aortic aneurysm by suppressing TXNIP-NLRP3 inflammasome

BACKGROUND: Preclinical studies have suggested that adipose-derived mesenchymal stem cells (ADSCs) transplantation can suppress abdominal aortic inflammation and aneurysm expansion through paracrine factors. Yet, the mechanism of action is not fully understood. In the present study, we further exami...

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Detalles Bibliográficos
Autores principales:	Hu, Jiateng, Jiang, Yihong, Wu, Xiaoyu, Wu, Zhaoyu, Qin, Jinbao, Zhao, Zhen, Li, Bo, Xu, Zhijue, Lu, Xinwu, Wang, Xin, Liu, Xiaobing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9327292/ https://www.ncbi.nlm.nih.gov/pubmed/35883151 http://dx.doi.org/10.1186/s13287-022-03037-1

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