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CD26 is a senescence marker associated with reduced immunopotency of human adipose tissue-derived multipotent mesenchymal stromal cells

INTRODUCTION: Human mesenchymal stromal cells (MSCs) have immunomodulatory, anti-inflammatory, and tolerogenic effects. Long-term in vitro expansion of MSCs to generate clinical grade products results in the accumulation of senescent-functionally impaired MSCs. Markers to assess the ‘senescent load’...

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Detalles Bibliográficos
Autores principales:	Psaroudis, Rose Triantafillia, Singh, Urvashi, Lora, Maximilien, Jeon, Peter, Boursiquot, Abigail, Stochaj, Ursula, Langlais, David, Colmegna, Inés
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9327293/ https://www.ncbi.nlm.nih.gov/pubmed/35883188 http://dx.doi.org/10.1186/s13287-022-03026-4

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