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Allelic complexity of KMT2A partial tandem duplications in acute myeloid leukemia and myelodysplastic syndromes

KMT2A partial tandem duplication (KMT2A-PTD) is an adverse risk factor in acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS), a potential therapeutic target, and an attractive marker of measurable residual disease. High initial KMT2A-PTD RNA levels have been linked to poor prognosis, bu...

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Detalles Bibliográficos
Autores principales:	Tsai, Harrison K., Gibson, Christopher J., Murdock, H. Moses, Davineni, Phani, Harris, Marian H., Wang, Eunice S., Gondek, Lukasz P., Kim, Annette S., Nardi, Valentina, Lindsley, R. Coleman
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Hematology 2022
Materias:	Stimulus Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9327559/ https://www.ncbi.nlm.nih.gov/pubmed/35584376 http://dx.doi.org/10.1182/bloodadvances.2022007613

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