A Novel Type I Interferon Primed Dendritic Cell Subpopulation in TREX1 Mutant Chilblain Lupus Patients

Heterozygous TREX1 mutations are associated with monogenic familial chilblain lupus and represent a risk factor for developing systemic lupus erythematosus. These interferonopathies originate from chronic type I interferon stimulation due to sensing of inadequately accumulating nucleic acids. We her...

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Detalles Bibliográficos
Autores principales: Eugster, Anne, Müller, Denise, Gompf, Anne, Reinhardt, Susanne, Lindner, Annett, Ashton, Michelle, Zimmermann, Nick, Beissert, Stefan, Bonifacio, Ezio, Günther, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9327789/
https://www.ncbi.nlm.nih.gov/pubmed/35911727
http://dx.doi.org/10.3389/fimmu.2022.897500

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