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SARS-CoV-2 nucleocapsid protein triggers hyperinflammation via protein-protein interaction-mediated intracellular Cl(−) accumulation in respiratory epithelium

SARS-CoV-2, the culprit pathogen of COVID-19, elicits prominent immune responses and cytokine storms. Intracellular Cl(−) is a crucial regulator of host defense, whereas the role of Cl(−) signaling pathway in modulating pulmonary inflammation associated with SARS-CoV-2 infection remains unclear. By...

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Detalles Bibliográficos
Autores principales:	Chen, Lei, Guan, Wei-Jie, Qiu, Zhuo-Er, Xu, Jian-Bang, Bai, Xu, Hou, Xiao-Chun, Sun, Jing, Qu, Su, Huang, Ze-Xin, Lei, Tian-Lun, Huang, Zi-Yang, Zhao, Jincun, Zhu, Yun-Xin, Ye, Ke-Nan, Lun, Zhao-Rong, Zhou, Wen-Liang, Zhong, Nan-Shan, Zhang, Yi-Lin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9328007/ https://www.ncbi.nlm.nih.gov/pubmed/35896532 http://dx.doi.org/10.1038/s41392-022-01048-1

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