The system’s genetics of depression and its somatic and mental comorbidities

Depression is a common mood disorder characterised by high comorbidity with other mental and somatic diseases. New studies reveal a shared genetic base for mental core symptoms and somatic comorbidities. Functional analyses showed multiple brain–body pathways involved. This may help considering new...

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Detalles Bibliográficos
Autores principales: Kalinichenko, Liubov S., Kornhuber, Johannes, Müller, Christian P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter 2022
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9328026/
https://www.ncbi.nlm.nih.gov/pubmed/35959215
http://dx.doi.org/10.1515/tnsci-2022-0229
Descripción
Sumario:Depression is a common mood disorder characterised by high comorbidity with other mental and somatic diseases. New studies reveal a shared genetic base for mental core symptoms and somatic comorbidities. Functional analyses showed multiple brain–body pathways involved. This may help considering new therapeutic approaches for depression as a system’s disorder.

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