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ICAM-1 on Breast Cancer Cells Suppresses Lung Metastasis but Is Dispensable for Tumor Growth and Killing by Cytotoxic T Cells

Breast tumors and their derived circulating cancer cells express the leukocyte β(2) integrin ligand Intercellular adhesion molecule 1 (ICAM-1). We found that elevated ICAM-1 expression in breast cancer cells results in a favorable outcome and prolonged survival of breast cancer patients. We therefor...

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Detalles Bibliográficos
Autores principales:	Regev, Ofer, Kizner, Marina, Roncato, Francesco, Dadiani, Maya, Saini, Massimo, Castro-Giner, Francesc, Yajuk, Olga, Kozlovski, Stav, Levi, Nehora, Addadi, Yoseph, Golani, Ofra, Ben-Dor, Shifra, Granot, Zvi, Aceto, Nicola, Alon, Ronen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9328178/ https://www.ncbi.nlm.nih.gov/pubmed/35911772 http://dx.doi.org/10.3389/fimmu.2022.849701

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