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Laminin N‐terminus α31 expression during development is lethal and causes widespread tissue‐specific defects in a transgenic mouse model

Laminins (LMs) are essential components of all basement membranes where they regulate an extensive array of tissue functions. Alternative splicing from the laminin α3 gene produces a non‐laminin but netrin‐like protein, Laminin N terminus α31 (LaNt α31). LaNt α31 is widely expressed in intact tissue...

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Detalles Bibliográficos
Autores principales: Sugden, Conor J., Iorio, Valentina, Troughton, Lee D., Liu, Ke, Morais, Mychel R. P. T., Lennon, Rachel, Bou‐Gharios, George, Hamill, Kevin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9328196/
https://www.ncbi.nlm.nih.gov/pubmed/35648586
http://dx.doi.org/10.1096/fj.202002588RRR