Cargando…

The human G protein‐coupled ATP receptor P2Y(11) is a target for anti‐inflammatory strategies

BACKGROUND AND PURPOSE: The ATP receptor P2Y(11), which couples to G(q) and G(s) proteins, senses cell stress and promotes cytoprotective responses. P2Y(11) receptors are upregulated during differentiation of M2 macrophages. However, it is unclear whether and how P2Y(11) receptors contribute to the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gruenbacher, Georg, Gander, Hubert, Dobler, Gabriele, Rahm, Andrea, Klaver, Dominik, Thurnher, Martin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Research Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9328440/ https://www.ncbi.nlm.nih.gov/pubmed/33463722 http://dx.doi.org/10.1111/bph.15379

Ejemplares similares

The Human G Protein-Coupled ATP Receptor P2Y(11) Is Associated With IL-10 Driven Macrophage Differentiation
por: Gruenbacher, Georg, et al.
Publicado: (2019)

The P2Y(11) receptor of human M2 macrophages activates canonical and IL-1 receptor signaling to translate the extracellular danger signal ATP into anti-inflammatory and pro-angiogenic responses
por: Klaver, Dominik, et al.
Publicado: (2022)

P2Y(11)/IL-1 receptor crosstalk controls macrophage inflammation: a novel target for anti-inflammatory strategies?
por: Klaver, Dominik, et al.
Publicado: (2023)

Intratumoral Th2 predisposition combines with an increased Th1 functional phenotype in clinical response to intravesical BCG in bladder cancer
por: Pichler, Renate, et al.
Publicado: (2016)

Mevalonate metabolism governs cancer immune surveillance
por: Gruenbacher, Georg, et al.
Publicado: (2017)

Mevalonate Metabolism in Immuno-Oncology
por: Gruenbacher, Georg, et al.
Publicado: (2017)

Mevalonate Metabolism in Cancer Stemness and Trained Immunity
por: Gruenbacher, Georg, et al.
Publicado: (2018)

Control of Macrophage Inflammation by P2Y Purinergic Receptors
por: Klaver, Dominik, et al.
Publicado: (2021)

G protein-coupled estrogen receptor mediates anti-inflammatory action in Crohn’s disease
por: Jacenik, Damian, et al.
Publicado: (2019)

The Essence of ATP Coupling
por: Bazhin, Nikolai
Publicado: (2012)

F-Type ATP Synthase Assembly Factors Atp11 and Atp12 in Arabidopsis
por: Duan, Zhikun, et al.
Publicado: (2020)

Roles of G protein-coupled receptors in inflammatory bowel disease
por: Zeng, Zhen, et al.
Publicado: (2020)

Adhesion G protein-coupled receptors in glioblastoma
por: Stephan, Gabriele, et al.
Publicado: (2021)

Estimating data-driven coronavirus disease 2019 mitigation strategies for safe university reopening
por: Yang, Qihui, et al.
Publicado: (2022)

G protein-coupled and ATP-sensitive inwardly rectifying potassium ion channels are essential for HIV entry
por: Dubey, Ravi C., et al.
Publicado: (2019)

Oracle 11g Anti-hacker's Cookbook
por: Neagu, Adrian
Publicado: (2012)

Modulation of the H(+)/ATP coupling ratio by ADP and ATP as a possible regulatory feature in the F-type ATP synthases
por: Turina, Paola
Publicado: (2022)

ATP Consumption Is Coupled with Endocytosis in Exudated Neutrophils
por: Wang, Duo, et al.
Publicado: (2023)

Utilizing GCaMP transgenic mice to monitor endogenous G(q/11)-coupled receptors
por: Partridge, John G.
Publicado: (2015)

Expression and function of proton-sensing G-protein-coupled receptors in inflammatory pain
por: Chen, Ying-Ju, et al.
Publicado: (2009)

G protein-coupled receptor 35: an emerging target in inflammatory and cardiovascular disease
por: Divorty, Nina, et al.
Publicado: (2015)

Fusion protein strategies for cryo-EM study of G protein-coupled receptors
por: Zhang, Kaihua, et al.
Publicado: (2022)

Shortage of Cellular ATP as a Cause of Diseases and Strategies to Enhance ATP
por: Johnson, Todd A., et al.
Publicado: (2019)

ATP/P2X7 receptor signaling as a potential anti-inflammatory target of natural polyphenols
por: Nuka, Erika, et al.
Publicado: (2018)

Ginsenoside Rg1 Exerts Anti-inflammatory Effects via G Protein-Coupled Estrogen Receptor in Lipopolysaccharide-Induced Microglia Activation
por: Gao, Xian-Qi, et al.
Publicado: (2019)

Screening of Optimal CpG-Oligodeoxynucleotide for Anti-Inflammatory Responses in the Avian Macrophage Cell Line HD11
por: Ichikawa, Kennosuke, et al.
Publicado: (2023)

G protein-coupled receptors /
Publicado: (2000)

G-Protein-Coupled Receptors
por: Thiriet, Marc
Publicado: (2011)

Mechanisms of ATP Release by Inflammatory Cells
por: Dosch, Michel, et al.
Publicado: (2018)

A coiled-coil-based design strategy for the thermostabilization of G-protein-coupled receptors
por: Amer, Marwa, et al.
Publicado: (2023)

Exploring pharmacological inhibition of G(q/11) as an analgesic strategy
por: Marwari, Subhi, et al.
Publicado: (2022)

Anti-Inflammatory Actions of G-Protein-Coupled Estrogen Receptor 1 (GPER) and Brain-Derived Estrogen Following Cerebral Ischemia in Ovariectomized Rats
por: Xu, Jing, et al.
Publicado: (2023)

Intracellular ATP in balance of pro- and anti-inflammatory cytokines in adipose tissue with and without tissue expansion
por: Lee, Jong Han, et al.
Publicado: (2017)

Purinergic ATP triggers moxibustion-induced local anti-nociceptive effect on inflammatory pain model
por: Yin, Hai-Yan, et al.
Publicado: (2021)

ATP evokes Ca(2+) signals in cultured foetal human cortical astrocytes entirely through G protein‐coupled P2Y receptors
por: Muller, Margit S., et al.
Publicado: (2017)

The Role of the “Anti-Inflammatory” Couple for the Management of Hyperuricemia With Deposition
por: Sansone, Andrea, et al.
Publicado: (2022)

CAR T-Cells Depend on the Coupling of NADH Oxidation with ATP Production
por: Garcia-Canaveras, Juan C., et al.
Publicado: (2021)

Inflammatory Biomarkers in Postural Orthostatic Tachycardia Syndrome with Elevated G-Protein-Coupled Receptor Autoantibodies
por: Gunning, William T., et al.
Publicado: (2021)

Vitamin D Status of Mice Deficient in Scavenger Receptor Class B Type 1, Cluster Determinant 36 and ATP-Binding Cassette Proteins G5/G8
por: Kiourtzidis, Mikis, et al.
Publicado: (2020)

Leptomeningeal form of Immunoglobulin G4-related hypertrophic meningitis with perivascular spread: a case report and review of the literature
por: Boban, Jasmina, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_nbn87vc7q086vmotprt84hjepf