Phytocannabinoid‐dependent mTORC1 regulation is dependent upon inositol polyphosphate multikinase activity

BACKGROUND AND PURPOSE: Cannabidiol (CBD) has been shown to differentially regulate the mechanistic target of rapamycin complex 1 (mTORC1) in preclinical models of disease, where it reduces activity in models of epilepsies and cancer and increases it in models of multiple sclerosis (MS) and psychosi...

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Detalles Bibliográficos
Autores principales: Damstra‐Oddy, Joseph L., Warren, Eleanor C., Perry, Christopher J., Desfougères, Yann, Fitzpatrick, John‐Mark K., Schaf, Judith, Costelloe, Lisa, Hind, William, Downer, Eric J., Saiardi, Adolfo, Williams, Robin S.B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9328663/
https://www.ncbi.nlm.nih.gov/pubmed/33347604
http://dx.doi.org/10.1111/bph.15351

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