Switch of serotonergic descending inhibition into facilitation by a spinal chloride imbalance in neuropathic pain

Descending control from the brain to the spinal cord shapes our pain experience, ranging from powerful analgesia to extreme sensitivity. Increasing evidence from both preclinical and clinical studies points to an imbalance toward descending facilitation as a substrate of pathological pain, but the u...

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Detalles Bibliográficos
Autores principales: Aby, Franck, Lorenzo, Louis-Etienne, Grivet, Zoé, Bouali-Benazzouz, Rabia, Martin, Hugo, Valerio, Stéphane, Whitestone, Sara, Isabel, Dominique, Idi, Walid, Bouchatta, Otmane, De Deurwaerdere, Philippe, Godin, Antoine G., Herry, Cyril, Fioramonti, Xavier, Landry, Marc, De Koninck, Yves, Fossat, Pascal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9328683/
https://www.ncbi.nlm.nih.gov/pubmed/35895817
http://dx.doi.org/10.1126/sciadv.abo0689

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