A non-transcriptional function of Yap regulates the DNA replication program in Xenopus laevis

In multicellular eukaryotic organisms, the initiation of DNA replication occurs asynchronously throughout S-phase according to a regulated replication timing program. Here, using Xenopus egg extracts, we showed that Yap (Yes-associated protein 1), a downstream effector of the Hippo signalling pathwa...

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Detalles Bibliográficos
Autores principales: Meléndez García, Rodrigo, Haccard, Olivier, Chesneau, Albert, Narassimprakash, Hemalatha, Roger, Jérôme, Perron, Muriel, Marheineke, Kathrin, Bronchain, Odile
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9328763/
https://www.ncbi.nlm.nih.gov/pubmed/35838349
http://dx.doi.org/10.7554/eLife.75741

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