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Weighing Potential Benefits and Harms of Mycoplasma genitalium Testing and Treatment Approaches

Since Mycoplasma genitalium was identified 40 years ago, much of the epidemiology has been described, diagnostic tests have been developed and approved, and recommended treatment approaches have been identified. However, the natural history remains incompletely understood, and antimicrobial resistan...

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Autores principales: Manhart, Lisa E., Geisler, William M., Bradshaw, Catriona S., Jensen, Jørgen S., Martin, David H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9328920/
https://www.ncbi.nlm.nih.gov/pubmed/35876565
http://dx.doi.org/10.3201/eid2808.220094
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author Manhart, Lisa E.
Geisler, William M.
Bradshaw, Catriona S.
Jensen, Jørgen S.
Martin, David H.
author_facet Manhart, Lisa E.
Geisler, William M.
Bradshaw, Catriona S.
Jensen, Jørgen S.
Martin, David H.
author_sort Manhart, Lisa E.
collection PubMed
description Since Mycoplasma genitalium was identified 40 years ago, much of the epidemiology has been described, diagnostic tests have been developed and approved, and recommended treatment approaches have been identified. However, the natural history remains incompletely understood, and antimicrobial resistance has rapidly increased. This review summarizes evidence published since the US Centers for Disease Control and Prevention 2015 Sexually Transmitted Diseases Treatment Guidelines. Data on sequelae remain insufficient, macrolide resistance is common, and fluoroquinolone resistance is increasing. Potential benefits of testing and treatment include resolving symptoms, interrupting transmission, and preventing sequelae. Potential harms include cost, patient anxiety, and increasing antimicrobial resistance.
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spelling pubmed-93289202022-08-06 Weighing Potential Benefits and Harms of Mycoplasma genitalium Testing and Treatment Approaches Manhart, Lisa E. Geisler, William M. Bradshaw, Catriona S. Jensen, Jørgen S. Martin, David H. Emerg Infect Dis Online Report Since Mycoplasma genitalium was identified 40 years ago, much of the epidemiology has been described, diagnostic tests have been developed and approved, and recommended treatment approaches have been identified. However, the natural history remains incompletely understood, and antimicrobial resistance has rapidly increased. This review summarizes evidence published since the US Centers for Disease Control and Prevention 2015 Sexually Transmitted Diseases Treatment Guidelines. Data on sequelae remain insufficient, macrolide resistance is common, and fluoroquinolone resistance is increasing. Potential benefits of testing and treatment include resolving symptoms, interrupting transmission, and preventing sequelae. Potential harms include cost, patient anxiety, and increasing antimicrobial resistance. Centers for Disease Control and Prevention 2022-08 /pmc/articles/PMC9328920/ /pubmed/35876565 http://dx.doi.org/10.3201/eid2808.220094 Text en https://creativecommons.org/licenses/by/4.0/Emerging Infectious Diseases is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Online Report
Manhart, Lisa E.
Geisler, William M.
Bradshaw, Catriona S.
Jensen, Jørgen S.
Martin, David H.
Weighing Potential Benefits and Harms of Mycoplasma genitalium Testing and Treatment Approaches
title Weighing Potential Benefits and Harms of Mycoplasma genitalium Testing and Treatment Approaches
title_full Weighing Potential Benefits and Harms of Mycoplasma genitalium Testing and Treatment Approaches
title_fullStr Weighing Potential Benefits and Harms of Mycoplasma genitalium Testing and Treatment Approaches
title_full_unstemmed Weighing Potential Benefits and Harms of Mycoplasma genitalium Testing and Treatment Approaches
title_short Weighing Potential Benefits and Harms of Mycoplasma genitalium Testing and Treatment Approaches
title_sort weighing potential benefits and harms of mycoplasma genitalium testing and treatment approaches
topic Online Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9328920/
https://www.ncbi.nlm.nih.gov/pubmed/35876565
http://dx.doi.org/10.3201/eid2808.220094
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