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A Systematic Review and Meta-Analysis on the Prognostic Value of BRCA Mutations, Homologous Recombination Gene Mutations, and Homologous Recombination Deficiencies in Cancer

Patients with BRCA1/2 mutations (BRCAm), loss-of-function mutations in other homologous recombination repair (HRRm) genes, or tumors that are homologous recombination deficiency positivity (HRD+) demonstrate a robust response to PARPi therapy. We conducted a systematic literature review and meta-ana...

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Detalles Bibliográficos
Autores principales:	Shao, Changxia, Chang, Michael S., Lam, Fred C., Marley, Andrew R., Tang, Huilin, Song, Yiqing, Miller, Chelsey, Brown, Madeline, Wan, Isabella, Han, Jiali, Adeboyeje, Gboyega
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9328957/ https://www.ncbi.nlm.nih.gov/pubmed/35909902 http://dx.doi.org/10.1155/2022/5830475

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