The Regulatory Effects of MicroRNAs on Tumor Immunity

MicroRNAs are endogenous noncoding small RNAs that posttranscriptionally regulate the expressions of their target genes. Accumulating research shows that miRNAs are crucial regulators of immune cell growth and antitumor immune response. Studies on miRNAs and tumors primarily focus on the tumor itsel...

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Detalles Bibliográficos
Autores principales: Lu, Yan, Deng, Muwen, Wang, Kang, Peng, Yuanhong, Ouyang, Manzhao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9329000/
https://www.ncbi.nlm.nih.gov/pubmed/35909469
http://dx.doi.org/10.1155/2022/2121993
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author Lu, Yan
Deng, Muwen
Wang, Kang
Peng, Yuanhong
Ouyang, Manzhao
author_facet Lu, Yan
Deng, Muwen
Wang, Kang
Peng, Yuanhong
Ouyang, Manzhao
author_sort Lu, Yan
collection PubMed
description MicroRNAs are endogenous noncoding small RNAs that posttranscriptionally regulate the expressions of their target genes. Accumulating research shows that miRNAs are crucial regulators of immune cell growth and antitumor immune response. Studies on miRNAs and tumors primarily focus on the tumor itself. At the same time, relatively few studies on the indirect regulatory effects of miRNAs in the development of tumors are achieved by affecting the immune system of tumor hosts and altering their immune responses. This review discusses the influence of miRNAs on the antitumor immune system.
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spelling pubmed-93290002022-07-28 The Regulatory Effects of MicroRNAs on Tumor Immunity Lu, Yan Deng, Muwen Wang, Kang Peng, Yuanhong Ouyang, Manzhao Biomed Res Int Review Article MicroRNAs are endogenous noncoding small RNAs that posttranscriptionally regulate the expressions of their target genes. Accumulating research shows that miRNAs are crucial regulators of immune cell growth and antitumor immune response. Studies on miRNAs and tumors primarily focus on the tumor itself. At the same time, relatively few studies on the indirect regulatory effects of miRNAs in the development of tumors are achieved by affecting the immune system of tumor hosts and altering their immune responses. This review discusses the influence of miRNAs on the antitumor immune system. Hindawi 2022-07-20 /pmc/articles/PMC9329000/ /pubmed/35909469 http://dx.doi.org/10.1155/2022/2121993 Text en Copyright © 2022 Yan Lu et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Lu, Yan
Deng, Muwen
Wang, Kang
Peng, Yuanhong
Ouyang, Manzhao
The Regulatory Effects of MicroRNAs on Tumor Immunity
title The Regulatory Effects of MicroRNAs on Tumor Immunity
title_full The Regulatory Effects of MicroRNAs on Tumor Immunity
title_fullStr The Regulatory Effects of MicroRNAs on Tumor Immunity
title_full_unstemmed The Regulatory Effects of MicroRNAs on Tumor Immunity
title_short The Regulatory Effects of MicroRNAs on Tumor Immunity
title_sort regulatory effects of micrornas on tumor immunity
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9329000/
https://www.ncbi.nlm.nih.gov/pubmed/35909469
http://dx.doi.org/10.1155/2022/2121993
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