Cargando…

Review: Precision Medicine Approaches for Genetic Cardiomyopathy: Targeting Phospholamban R14del

PURPOSE OF REVIEW: Heart failure is a syndrome with poor prognosis and no curative options for the majority of patients. The standard one-size-fits-all-treatment approach, targeting neurohormonal dysregulations, helps to modulate symptoms of heart failure, but fails to address the cause of the probl...

Descripción completa

Detalles Bibliográficos
Autores principales:	Deiman, Frederik E., Bomer, Nils, van der Meer, Peter, Grote Beverborg, Niels
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2022
Materias:	Translational Research in Heart Failure (M. Hoes, Section Editor)
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9329159/ https://www.ncbi.nlm.nih.gov/pubmed/35699837 http://dx.doi.org/10.1007/s11897-022-00558-x

Ejemplares similares

Mitochondria as Therapeutic Targets in Heart Failure
por: Schwemmlein, Julia, et al.
Publicado: (2022)

Change of Heart: the Epitranscriptome of Small Non-coding RNAs in Heart Failure
por: Woudenberg, Tamar, et al.
Publicado: (2022)

Arrhythmogenic Cardiomyopathy: A Disease or Merely a Phenotype?
por: Protonotarios, Alexandros, et al.
Publicado: (2020)

Selenium, Selenoproteins, and Heart Failure: Current Knowledge and Future Perspective
por: Al-Mubarak, Ali A., et al.
Publicado: (2021)

Phospholamban antisense oligonucleotides improve cardiac function in murine cardiomyopathy
por: Grote Beverborg, Niels, et al.
Publicado: (2021)

Antisense Therapy Attenuates Phospholamban p.(Arg14del) Cardiomyopathy in Mice and Reverses Protein Aggregation
por: Eijgenraam, Tim R., et al.
Publicado: (2022)

Potential genetic predisposition for anthracycline-associated cardiomyopathy in families with dilated cardiomyopathy
por: Wasielewski, Marijke, et al.
Publicado: (2014)

Significant reduction of left atrial volume concomitant with clinical improvement after percutaneous transluminal septal myocardial ablation for drug-refractory hypertrophic obstructive cardiomyopathy, and its precise detection with multidetector CT
por: Maekawa, Yuichiro, et al.
Publicado: (2016)

Exercise and myocardial injury in hypertrophic cardiomyopathy
por: Cramer, G Etienne, et al.
Publicado: (2020)

Copper chelation in patients with hypertrophic cardiomyopathy
por: Reid, Anna, et al.
Publicado: (2022)

Factors influencing long-term heart failure mortality in patients with obstructive hypertrophic cardiomyopathy in Western Sweden: probable dose-related protection from beta-blocker therapy
por: Javidgonbadi, Davood, et al.
Publicado: (2019)

Biomarkers of cardiovascular stress and fibrosis in preclinical hypertrophic cardiomyopathy
por: Ho, Jennifer E, et al.
Publicado: (2017)

Nationwide prevalence and characteristics of transthyretin amyloid cardiomyopathy in Sweden
por: Lauppe, Rosa Elisabeth, et al.
Publicado: (2021)

Clinical presentations leading to arrhythmogenic left ventricular cardiomyopathy
por: Graziosi, Maddalena, et al.
Publicado: (2022)

Rationale and design of the preserved versus reduced ejection fraction biomarker registry and precision medicine database for ambulatory patients with heart failure (PREFER-HF) study
por: Abboud, Andrew, et al.
Publicado: (2021)

Clinical, ECG and echocardiographic clues to the diagnosis of TTR-related cardiomyopathy
por: Damy, Thibaud, et al.
Publicado: (2016)

Results of comprehensive diagnostic work-up in ‘idiopathic’ dilated cardiomyopathy
por: Broch, Kaspar, et al.
Publicado: (2015)

Sarcomere mutation negative hypertrophic cardiomyopathy is associated with ageing and obesity
por: de Feria, Alejandro E, et al.
Publicado: (2021)

Direct and indirect effect of the COVID-19 pandemic on patients with cardiomyopathy
por: Hammersley, Daniel J, et al.
Publicado: (2022)

Repetitive squatting exercise as a diagnostic predictor in patients with dilated cardiomyopathy
por: Sveric, Krunoslav Michael, et al.
Publicado: (2018)

Systematic review and meta-analysis of prolactin and iron deficiency in peripartum cardiomyopathy
por: Cherubin, Sinaida, et al.
Publicado: (2020)

Stress-Induced Cardiomyopathy Precipitated by COVID-19 and Influenza A Coinfection
por: Sang, Charlie Joseph, et al.
Publicado: (2020)

Inline perfusion mapping provides insights into the disease mechanism in hypertrophic cardiomyopathy
por: Camaioni, Claudia, et al.
Publicado: (2020)

Aetiological and morphological spectrum of cardiomyopathies in French Guiana: a retrospective study
por: Leménager, Paul, et al.
Publicado: (2020)

Mutations in TRIM63 cause an autosomal-recessive form of hypertrophic cardiomyopathy
por: Salazar-Mendiguchía, Joel, et al.
Publicado: (2020)

Management of Acute Myocarditis and Chronic Inflammatory Cardiomyopathy: An Expert Consensus Document
por: Ammirati, Enrico, et al.
Publicado: (2020)

Association between right ventricular strain and outcomes in patients with dilated cardiomyopathy
por: Liu, Tong, et al.
Publicado: (2021)

Moderate excess alcohol consumption and adverse cardiac remodelling in dilated cardiomyopathy
por: Tayal, Upasana, et al.
Publicado: (2022)

Prognostic impact of blood pressure response plus gadolinium enhancement in dilated cardiomyopathy
por: Tateishi, Emi, et al.
Publicado: (2015)

Stress-coping skills and neuroticism in apical ballooning syndrome (Takotsubo/stress cardiomyopathy)
por: Scantlebury, Dawn C, et al.
Publicado: (2016)

Cardiovascular magnetic resonance T2* mapping for the assessment of cardiovascular events in hypertrophic cardiomyopathy
por: Gastl, Mareike, et al.
Publicado: (2020)

Cardiomyopathy associated with the Ala143Thr variant of the α-galactosidase A gene
por: Valtola, Kati, et al.
Publicado: (2020)

Clinical profile and prognostic factors of alcoholic cardiomyopathy in tribal and non-tribal population
por: Dungdung, Ajit, et al.
Publicado: (2020)

ECG characteristics according to the presence of late gadolinium enhancement on cardiac MRI in hypertrophic cardiomyopathy
por: Grall, Sylvain, et al.
Publicado: (2014)

The influence of aortoseptal angulation on provocable left ventricular outflow tract obstruction in hypertrophic cardiomyopathy
por: Critoph, Christopher Howell, et al.
Publicado: (2014)

Novel genotype–phenotype associations demonstrated by high-throughput sequencing in patients with hypertrophic cardiomyopathy
por: Lopes, Luis R, et al.
Publicado: (2015)

Demographic features and prevalence of myocarditis in patients undergoing transarterial endomyocardial biopsy for unexplained cardiomyopathy
por: Hassan, Ayman K.M., et al.
Publicado: (2017)

Prognostic value of plasma big endothelin-1 in left ventricular non-compaction cardiomyopathy
por: Fan, Peng, et al.
Publicado: (2021)

CMR feature tracking in patients with dilated cardiomyopathy: patterns of myocardial strain and focal fibrosis
por: Chevalier, Céleste, et al.
Publicado: (2022)

Characteristics and outcome of patients with COVID-19 complicated by Takotsubo cardiomyopathy: case series with literature review
por: Hegde, Shruti, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_aiesacgufvk3b39fu5iqoitglg