Increasing nitric oxide bioavailability fails to improve collateral vessel formation in humanized sickle cell mice

Sickle cell disease (SCD) is associated with repeated bouts of vascular insufficiency leading to organ dysfunction. Deficits in revascularization following vascular injury are evident in SCD patients and animal models. We aimed to elucidate whether enhancing nitric oxide bioavailability in SCD mice...

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Detalles Bibliográficos
Autores principales: Lewis, Caitlin V, Sellak, Hassan, Hansen, Laura, Joseph, Giji, Hurtado, Julian, Archer, David R, Jun, Ho-Wook, Brown, Lou Ann, Taylor, W. Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9329194/
https://www.ncbi.nlm.nih.gov/pubmed/35354915
http://dx.doi.org/10.1038/s41374-022-00780-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9329194/
https://www.ncbi.nlm.nih.gov/pubmed/35354915
http://dx.doi.org/10.1038/s41374-022-00780-0

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