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Ribosome selectivity and nascent chain context in modulating the incorporation of fluorescent non-canonical amino acid into proteins

Fluorescence reporter groups are important tools to study the structure and dynamics of proteins. Genetic code reprogramming allows for cotranslational incorporation of non-canonical amino acids at any desired position. However, cotranslational incorporation of bulky fluorescence reporter groups is...

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Detalles Bibliográficos
Autores principales: Thommen, Michael, Draycheva, Albena, Rodnina, Marina V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9329280/
https://www.ncbi.nlm.nih.gov/pubmed/35896582
http://dx.doi.org/10.1038/s41598-022-16932-7