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Decoding kinase-adverse event associations for small molecule kinase inhibitors

Small molecule kinase inhibitors (SMKIs) are being approved at a fast pace under expedited programs for anticancer treatment. In this study, we construct a multi-domain dataset from a total of 4638 patients in the registrational trials of 16 FDA-approved SMKIs and employ a machine-learning model to...

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Detalles Bibliográficos
Autores principales:	Gong, Xiajing, Hu, Meng, Liu, Jinzhong, Kim, Geoffrey, Xu, James, McKee, Amy, Palmby, Todd, de Claro, R. Angelo, Zhao, Liang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9329312/ https://www.ncbi.nlm.nih.gov/pubmed/35896580 http://dx.doi.org/10.1038/s41467-022-32033-5

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