Dietary protein increases T-cell-independent sIgA production through changes in gut microbiota-derived extracellular vesicles

Secretory IgA is a key mucosal component ensuring host-microbiota mutualism. Here we use nutritional geometry modelling in mice fed 10 different macronutrient-defined, isocaloric diets, and identify dietary protein as the major driver of secretory IgA production. Protein-driven secretory IgA inducti...

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Detalles Bibliográficos
Autores principales: Tan, Jian, Ni, Duan, Taitz, Jemma, Pinget, Gabriela Veronica, Read, Mark, Senior, Alistair, Wali, Jibran Abdul, Elnour, Reem, Shanahan, Erin, Wu, Huiling, Chadban, Steven J., Nanan, Ralph, King, Nicholas Jonathan Cole, Grau, Georges Emile, Simpson, Stephen J., Macia, Laurence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9329401/
https://www.ncbi.nlm.nih.gov/pubmed/35896537
http://dx.doi.org/10.1038/s41467-022-31761-y

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