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Infusion of etoposide in the CA1 disrupts hippocampal immediate early gene expression and hippocampus-dependent learning

Tight regulation of immediate early gene (IEG) expression is important for synaptic plasticity, learning, and memory. Recent work has suggested that DNA double strand breaks (DSBs) may have an adaptive role in post-mitotic cells to induce IEG expression. Physiological activity in cultured neurons as...

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Detalles Bibliográficos
Autores principales:	Boutros, Sydney Weber, Kessler, Kat, Unni, Vivek K., Raber, Jacob
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9329441/ https://www.ncbi.nlm.nih.gov/pubmed/35896679 http://dx.doi.org/10.1038/s41598-022-17052-y

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