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Eicosapentaenoic acid (EPA)-induced inhibitory effects on porcine coronary and cerebral arteries involve inhibition of prostanoid TP receptors

This study was performed to elucidate whether eicosapentaenoic acid (EPA) suppresses spasm-prone blood vessel contractions induced by a thromboxane mimetic (U46619) and prostaglandin F(2α) (PGF(2α)) and determine whether the primary target of EPA is the prostanoid TP receptor. Accordingly, we assess...

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Detalles Bibliográficos
Autores principales: Yoshioka, Kento, Obara, Keisuke, Oikawa, Shunya, Uemura, Kohei, Yamaguchi, Akina, Fujisawa, Kazuki, Hanazawa, Hitomi, Fujiwara, Miki, Endoh, Taison, Suzuki, Taichi, De Dios Regadera, Montserrat, Ito, Daichi, Saitoh, Noboru, Nakagome, Yutaka, Yamashita, Toma, Kiguchi, Mayu, Saito, Yuka, Nakao, Yuri, Miyaji, Hinako, Ou, Guanghan, Xu, Keyue, Tanaka, Yoshio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9329469/
https://www.ncbi.nlm.nih.gov/pubmed/35896794
http://dx.doi.org/10.1038/s41598-022-16917-6