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Investigating the Mechanism of Germinal Center Shutdown

Germinal centers (GCs) are transient structures where affinity maturation of B cells gives rise to high affinity plasma and memory cells. The mechanism of GC shutdown is unclear, despite being an important phenomenon maintaining immune homeostasis. In this study, we used a mathematical model to iden...

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Detalles Bibliográficos
Autores principales: Arulraj, Theinmozhi, Binder, Sebastian C., Meyer-Hermann, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9329532/
https://www.ncbi.nlm.nih.gov/pubmed/35911680
http://dx.doi.org/10.3389/fimmu.2022.922318