Cargando…

Endovascular surgery for thoracic aortic pathologies involving the aortic arch

BACKGROUND: Aortic arch pathologies are serious clinical conditions associated with a very dismal prognosis. Traditional open surgery has a high mortality and is not suitable for critically ill patients. Recently years, endovascular treatment of thoracic aorta has made rapid progress and has been gr...

Descripción completa

Detalles Bibliográficos
Autores principales: Lu, Heng, Huang, Ling-chen, Chen, Liang-wan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9329620/
https://www.ncbi.nlm.nih.gov/pubmed/35911538
http://dx.doi.org/10.3389/fcvm.2022.927592
_version_ 1784757957380014080
author Lu, Heng
Huang, Ling-chen
Chen, Liang-wan
author_facet Lu, Heng
Huang, Ling-chen
Chen, Liang-wan
author_sort Lu, Heng
collection PubMed
description BACKGROUND: Aortic arch pathologies are serious clinical conditions associated with a very dismal prognosis. Traditional open surgery has a high mortality and is not suitable for critically ill patients. Recently years, endovascular treatment of thoracic aorta has made rapid progress and has been gradually applied to the treatment of aortic arch pathologies. However, maintaining cerebral blood flow during endovascular treatment of aortic arch lesions remains a challenge at this time. This study aims to evaluate the feasibility, efficacy, and safety of endovascular treatment of thoracic aortic pathologies involving the aortic arch, and to present initial experience with this technique. METHODS: From October 2016 to December 2020, patients who met the inclusion criteria were enrolled. All patients underwent thoracic endovascular aortic repair with the proximal landing zone of the stent-graft in the aortic arch at Ishimaru zones 0–1, in which cerebral flow needs to be maintained during surgery, and the supra-aortic branches were reconstruction with either in situ fenestration or the chimney technique. RESULTS: A total of 62 cases with lesions involving the arch were treated with endovascular surgery. Total supra-aortic branches reconstruction was successfully performed in 51 cases, the left carotid artery (LCA) and the innominate artery reconstruction were performed in eight cases, the left subclavian artery (LSA) and the LCA were reconstructed in three patients. Among them, the in situ fenestration or chimney repair technique for the LSA was successful performed in 42 and 12 cases. However, in 20 patients, attempts to reconstruction the LSA using the fenestration technique were unsuccessful due to tortuous and angulated vessels. Early mortality was 6.45%. No neurological complications related to surgery occurred. Computer tomography images at post-operative follow-up (mean 3.51 months) confirmed patency of all branch stents without any signs of endoleaks, migration, conversion to retrograde dissection or receive open-heart surgery. CONCLUSION: The endovascular technique is an effective, feasible, safe and repeatable method to reconstruct the aortic arch, which allows for the reconstruction of the supra-aortic branches.
format Online
Article
Text
id pubmed-9329620
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Frontiers Media S.A.
record_format MEDLINE/PubMed
spelling pubmed-93296202022-07-29 Endovascular surgery for thoracic aortic pathologies involving the aortic arch Lu, Heng Huang, Ling-chen Chen, Liang-wan Front Cardiovasc Med Cardiovascular Medicine BACKGROUND: Aortic arch pathologies are serious clinical conditions associated with a very dismal prognosis. Traditional open surgery has a high mortality and is not suitable for critically ill patients. Recently years, endovascular treatment of thoracic aorta has made rapid progress and has been gradually applied to the treatment of aortic arch pathologies. However, maintaining cerebral blood flow during endovascular treatment of aortic arch lesions remains a challenge at this time. This study aims to evaluate the feasibility, efficacy, and safety of endovascular treatment of thoracic aortic pathologies involving the aortic arch, and to present initial experience with this technique. METHODS: From October 2016 to December 2020, patients who met the inclusion criteria were enrolled. All patients underwent thoracic endovascular aortic repair with the proximal landing zone of the stent-graft in the aortic arch at Ishimaru zones 0–1, in which cerebral flow needs to be maintained during surgery, and the supra-aortic branches were reconstruction with either in situ fenestration or the chimney technique. RESULTS: A total of 62 cases with lesions involving the arch were treated with endovascular surgery. Total supra-aortic branches reconstruction was successfully performed in 51 cases, the left carotid artery (LCA) and the innominate artery reconstruction were performed in eight cases, the left subclavian artery (LSA) and the LCA were reconstructed in three patients. Among them, the in situ fenestration or chimney repair technique for the LSA was successful performed in 42 and 12 cases. However, in 20 patients, attempts to reconstruction the LSA using the fenestration technique were unsuccessful due to tortuous and angulated vessels. Early mortality was 6.45%. No neurological complications related to surgery occurred. Computer tomography images at post-operative follow-up (mean 3.51 months) confirmed patency of all branch stents without any signs of endoleaks, migration, conversion to retrograde dissection or receive open-heart surgery. CONCLUSION: The endovascular technique is an effective, feasible, safe and repeatable method to reconstruct the aortic arch, which allows for the reconstruction of the supra-aortic branches. Frontiers Media S.A. 2022-07-14 /pmc/articles/PMC9329620/ /pubmed/35911538 http://dx.doi.org/10.3389/fcvm.2022.927592 Text en Copyright © 2022 Lu, Huang and Chen. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Cardiovascular Medicine
Lu, Heng
Huang, Ling-chen
Chen, Liang-wan
Endovascular surgery for thoracic aortic pathologies involving the aortic arch
title Endovascular surgery for thoracic aortic pathologies involving the aortic arch
title_full Endovascular surgery for thoracic aortic pathologies involving the aortic arch
title_fullStr Endovascular surgery for thoracic aortic pathologies involving the aortic arch
title_full_unstemmed Endovascular surgery for thoracic aortic pathologies involving the aortic arch
title_short Endovascular surgery for thoracic aortic pathologies involving the aortic arch
title_sort endovascular surgery for thoracic aortic pathologies involving the aortic arch
topic Cardiovascular Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9329620/
https://www.ncbi.nlm.nih.gov/pubmed/35911538
http://dx.doi.org/10.3389/fcvm.2022.927592
work_keys_str_mv AT luheng endovascularsurgeryforthoracicaorticpathologiesinvolvingtheaorticarch
AT huanglingchen endovascularsurgeryforthoracicaorticpathologiesinvolvingtheaorticarch
AT chenliangwan endovascularsurgeryforthoracicaorticpathologiesinvolvingtheaorticarch