SR9009 improves heart function after pressure overload independent of cardiac REV-ERB

The core clock component REV-ERB is essential for heart function. Previous studies show that REV-ERB agonist SR9009 ameliorates heart remodeling in the pressure overload model with transverse aortic constriction (TAC). However, it is unknown whether SR9009 indeed works through cardiac REV-ERB, given...

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Detalles Bibliográficos
Autores principales: Li, Hui, Song, Shiyang, Tien, Chih-liang, Qi, Lei, Graves, Andrea, Nasiotis, Eleni, Burris, Thomas P., Zhao, Yuanbiao, Sun, Zheng, Zhang, Lilei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cardiovascular Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9329699/
https://www.ncbi.nlm.nih.gov/pubmed/35911512
http://dx.doi.org/10.3389/fcvm.2022.952114

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9329699/
https://www.ncbi.nlm.nih.gov/pubmed/35911512
http://dx.doi.org/10.3389/fcvm.2022.952114

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