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SR9009 improves heart function after pressure overload independent of cardiac REV-ERB

The core clock component REV-ERB is essential for heart function. Previous studies show that REV-ERB agonist SR9009 ameliorates heart remodeling in the pressure overload model with transverse aortic constriction (TAC). However, it is unknown whether SR9009 indeed works through cardiac REV-ERB, given...

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Detalles Bibliográficos
Autores principales:	Li, Hui, Song, Shiyang, Tien, Chih-liang, Qi, Lei, Graves, Andrea, Nasiotis, Eleni, Burris, Thomas P., Zhao, Yuanbiao, Sun, Zheng, Zhang, Lilei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Cardiovascular Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9329699/ https://www.ncbi.nlm.nih.gov/pubmed/35911512 http://dx.doi.org/10.3389/fcvm.2022.952114

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