Portal vein thrombosis as a thrombotic complication of COVID-19 mRNA vaccine: A case report and literature review

Thrombosis following COVID-19 vaccination commonly occurs with vector-based vaccines. The proposed mechanism is vaccine-induced thrombotic thrombocytopenia (VITT), with thrombocytopenia as principal manifestation. We present a 51-year-old male who came with isolated portal vein thrombosis (PVT) one...

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Detalles Bibliográficos
Autores principales: Shrestha, Prakriti Singh, Ishak, Angela, Napit, Arun R., Sarwar, Sarosh, Rai, Niraj, Nizami, Zoha, Bheemisetty, Niharika, Jayaraj, Prashanth, Shrestha, Amardeep, Rodriguez, Ivan D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9329705/
https://www.ncbi.nlm.nih.gov/pubmed/35915737
http://dx.doi.org/10.1016/j.idcr.2022.e01582
Descripción
Sumario:Thrombosis following COVID-19 vaccination commonly occurs with vector-based vaccines. The proposed mechanism is vaccine-induced thrombotic thrombocytopenia (VITT), with thrombocytopenia as principal manifestation. We present a 51-year-old male who came with isolated portal vein thrombosis (PVT) one day after Moderna vaccination, without associated thrombocytopenia, challenging VITT as being the only patho-mechanism. Further exploration of these possible alternative mechanisms is needed for COVID-19 vaccine-related thrombotic complications.

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