Portal vein thrombosis as a thrombotic complication of COVID-19 mRNA vaccine: A case report and literature review

Thrombosis following COVID-19 vaccination commonly occurs with vector-based vaccines. The proposed mechanism is vaccine-induced thrombotic thrombocytopenia (VITT), with thrombocytopenia as principal manifestation. We present a 51-year-old male who came with isolated portal vein thrombosis (PVT) one...

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Autores principales: Shrestha, Prakriti Singh, Ishak, Angela, Napit, Arun R., Sarwar, Sarosh, Rai, Niraj, Nizami, Zoha, Bheemisetty, Niharika, Jayaraj, Prashanth, Shrestha, Amardeep, Rodriguez, Ivan D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9329705/
https://www.ncbi.nlm.nih.gov/pubmed/35915737
http://dx.doi.org/10.1016/j.idcr.2022.e01582
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author Shrestha, Prakriti Singh
Ishak, Angela
Napit, Arun R.
Sarwar, Sarosh
Rai, Niraj
Nizami, Zoha
Bheemisetty, Niharika
Jayaraj, Prashanth
Shrestha, Amardeep
Rodriguez, Ivan D.
author_facet Shrestha, Prakriti Singh
Ishak, Angela
Napit, Arun R.
Sarwar, Sarosh
Rai, Niraj
Nizami, Zoha
Bheemisetty, Niharika
Jayaraj, Prashanth
Shrestha, Amardeep
Rodriguez, Ivan D.
author_sort Shrestha, Prakriti Singh
collection PubMed
description Thrombosis following COVID-19 vaccination commonly occurs with vector-based vaccines. The proposed mechanism is vaccine-induced thrombotic thrombocytopenia (VITT), with thrombocytopenia as principal manifestation. We present a 51-year-old male who came with isolated portal vein thrombosis (PVT) one day after Moderna vaccination, without associated thrombocytopenia, challenging VITT as being the only patho-mechanism. Further exploration of these possible alternative mechanisms is needed for COVID-19 vaccine-related thrombotic complications.
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spelling pubmed-93297052022-07-28 Portal vein thrombosis as a thrombotic complication of COVID-19 mRNA vaccine: A case report and literature review Shrestha, Prakriti Singh Ishak, Angela Napit, Arun R. Sarwar, Sarosh Rai, Niraj Nizami, Zoha Bheemisetty, Niharika Jayaraj, Prashanth Shrestha, Amardeep Rodriguez, Ivan D. IDCases Case Report Thrombosis following COVID-19 vaccination commonly occurs with vector-based vaccines. The proposed mechanism is vaccine-induced thrombotic thrombocytopenia (VITT), with thrombocytopenia as principal manifestation. We present a 51-year-old male who came with isolated portal vein thrombosis (PVT) one day after Moderna vaccination, without associated thrombocytopenia, challenging VITT as being the only patho-mechanism. Further exploration of these possible alternative mechanisms is needed for COVID-19 vaccine-related thrombotic complications. Elsevier 2022-07-26 /pmc/articles/PMC9329705/ /pubmed/35915737 http://dx.doi.org/10.1016/j.idcr.2022.e01582 Text en © 2022 The Authors. Published by Elsevier Ltd. https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Shrestha, Prakriti Singh
Ishak, Angela
Napit, Arun R.
Sarwar, Sarosh
Rai, Niraj
Nizami, Zoha
Bheemisetty, Niharika
Jayaraj, Prashanth
Shrestha, Amardeep
Rodriguez, Ivan D.
Portal vein thrombosis as a thrombotic complication of COVID-19 mRNA vaccine: A case report and literature review
title Portal vein thrombosis as a thrombotic complication of COVID-19 mRNA vaccine: A case report and literature review
title_full Portal vein thrombosis as a thrombotic complication of COVID-19 mRNA vaccine: A case report and literature review
title_fullStr Portal vein thrombosis as a thrombotic complication of COVID-19 mRNA vaccine: A case report and literature review
title_full_unstemmed Portal vein thrombosis as a thrombotic complication of COVID-19 mRNA vaccine: A case report and literature review
title_short Portal vein thrombosis as a thrombotic complication of COVID-19 mRNA vaccine: A case report and literature review
title_sort portal vein thrombosis as a thrombotic complication of covid-19 mrna vaccine: a case report and literature review
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9329705/
https://www.ncbi.nlm.nih.gov/pubmed/35915737
http://dx.doi.org/10.1016/j.idcr.2022.e01582
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