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The Role of Epigenetic Change in Therapy-Induced Neuroendocrine Prostate Cancer Lineage Plasticity

The androgen receptor (AR) signaling pathway is critical for growth and differentiation of prostate cancer cells. For that reason, androgen deprivation therapy with medical or surgical castration is the principal treatment for metastatic prostate cancer. More recently, new potent AR signaling inhibi...

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Detalles Bibliográficos
Autores principales:	Storck, William K., May, Allison M., Westbrook, Thomas C., Duan, Zhi, Morrissey, Colm, Yates, Joel A., Alumkal, Joshi J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Endocrinology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9329809/ https://www.ncbi.nlm.nih.gov/pubmed/35909568 http://dx.doi.org/10.3389/fendo.2022.926585

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