Cargando…

The Role of Epigenetic Change in Therapy-Induced Neuroendocrine Prostate Cancer Lineage Plasticity

The androgen receptor (AR) signaling pathway is critical for growth and differentiation of prostate cancer cells. For that reason, androgen deprivation therapy with medical or surgical castration is the principal treatment for metastatic prostate cancer. More recently, new potent AR signaling inhibi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Storck, William K., May, Allison M., Westbrook, Thomas C., Duan, Zhi, Morrissey, Colm, Yates, Joel A., Alumkal, Joshi J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Endocrinology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9329809/ https://www.ncbi.nlm.nih.gov/pubmed/35909568 http://dx.doi.org/10.3389/fendo.2022.926585

Ejemplares similares

Lineage plasticity and treatment resistance in prostate cancer: the intersection of genetics, epigenetics, and evolution
por: Imamura, Jarrell, et al.
Publicado: (2023)

BET Bromodomain Inhibition Blocks an AR-Repressed, E2F1-Activated Treatment-Emergent Neuroendocrine Prostate Cancer Lineage Plasticity Program
por: Kim, Dae-Hwan, et al.
Publicado: (2021)

Alternative splicing of LSD1+8a in neuroendocrine prostate cancer is mediated by SRRM4
por: Coleman, Daniel J., et al.
Publicado: (2020)

Tribbles 2 pseudokinase confers enzalutamide resistance in prostate cancer by promoting lineage plasticity
por: Monga, Jitender, et al.
Publicado: (2021)

Clinical Epigenetics of Neuroendocrine Tumors: The Road Ahead
por: Colao, Annamaria, et al.
Publicado: (2020)

Endocrine and paracrine characteristics of neuroendocrine prostate cancer
por: Arman, Tarana, et al.
Publicado: (2022)

Epigenetic regulation of SST(2) expression in small intestinal neuroendocrine tumors
por: Klomp, Maria J., et al.
Publicado: (2023)

MUC1-C regulates lineage plasticity driving progression to neuroendocrine prostate cancer
por: Yasumizu, Yota, et al.
Publicado: (2020)

Transcriptional profiling of matched patient biopsies clarifies molecular determinants of enzalutamide-induced lineage plasticity
por: Westbrook, Thomas C., et al.
Publicado: (2022)

LSD1 promotes prostate cancer reprogramming by repressing TP53 signaling independently of its demethylase function
por: Kumaraswamy, Anbarasu, et al.
Publicado: (2023)

ZBTB7A as a novel vulnerability in neuroendocrine prostate cancer
por: Bae, Song Yi, et al.
Publicado: (2023)

De novo induction of lineage plasticity from human prostate luminal epithelial cells by activated AKT1 and c-Myc
por: Kwon, Oh-Joon, et al.
Publicado: (2020)

Author Correction: MUC1-C regulates lineage plasticity driving progression to neuroendocrine prostate cancer
por: Yasumizu, Yota, et al.
Publicado: (2020)

Novel biomarkers predict prognosis and drug-induced neuroendocrine differentiation in patients with prostate cancer
por: Lin, Jingwei, et al.
Publicado: (2023)

Subtype heterogeneity and epigenetic convergence in neuroendocrine prostate cancer
por: Cejas, Paloma, et al.
Publicado: (2021)

Adipose Tissue Myeloid-Lineage Neuroimmune Cells Express Genes Important for Neural Plasticity and Regulate Adipose Innervation
por: Blaszkiewicz, Magdalena, et al.
Publicado: (2022)

Neuroendocrine Carcinoma as an Independent Prognostic Factor for Patients With Prostate Cancer: A Population-Based Study
por: Yao, Jiping, et al.
Publicado: (2021)

A Case of an Immature PIT1-Lineage Pituitary Neuroendocrine Tumor of the Nasopharynx
por: Peters, Jessica, et al.
Publicado: (2023)

Concurrent Targeting of HDAC and PI3K to Overcome Phenotypic Heterogeneity of Castration-resistant and Neuroendocrine Prostate Cancers
por: Zhang, Ailin, et al.
Publicado: (2023)

Programming of neuroendocrine self in the thymus and its defect in the development of neuroendocrine autoimmunity
por: Geenen, Vincent, et al.
Publicado: (2013)

Molecular Testing Identifies Determinants of Exceptional Response and Guides Precision Therapy in a Patient with Lethal, Treatment-emergent Neuroendocrine Prostate Cancer
por: Turina, Claire B, et al.
Publicado: (2019)

Neuroendocrine Role for VGF
por: Lewis, Jo E., et al.
Publicado: (2015)

Transcriptional and Epigenetic Regulation of Context-Dependent Plasticity in T-Helper Lineages
por: Friedman, Meyer J., et al.
Publicado: (2023)

Multi-Omics Analyses Detail Metabolic Reprogramming in Lipids, Carnitines, and Use of Glycolytic Intermediates between Prostate Small Cell Neuroendocrine Carcinoma and Prostate Adenocarcinoma
por: Gao, Bei, et al.
Publicado: (2019)

Lineage Plasticity in SCLC Generates Non-Neuroendocrine Cells Primed for Vasculogenic Mimicry
por: Pearsall, Sarah M., et al.
Publicado: (2023)

Ex Vivo Modeling of Human Neuroendocrine Tumors in Tissue Surrogates
por: Herring, Brendon, et al.
Publicado: (2021)

Nomogram for preoperative estimation of histologic grade in gastrointestinal neuroendocrine tumors
por: Wu, Zhi-Qi, et al.
Publicado: (2022)

Neuroendocrine regulation of female aggression
por: Oliveira, Vinícius Elias de Moura, et al.
Publicado: (2022)

Neuroendocrine regulation of appetitive ingestive behavior
por: Keen-Rhinehart, Erin, et al.
Publicado: (2013)

The Regulated Secretory Pathway in Neuroendocrine Cells
por: Vazquez-Martinez, Rafael, et al.
Publicado: (2014)

Reproductive Neuroendocrine Pathways of Social Behavior
por: Parhar, Ishwar S., et al.
Publicado: (2016)

Editorial: Neuroendocrine Control of Feeding Behavior
por: Luquet, Serge H., et al.
Publicado: (2019)

Diabetes in Patients With Pancreatic Neuroendocrine Neoplasms
por: Zhuge, Xiaoling, et al.
Publicado: (2020)

Engineering Lineage Potency and Plasticity of Stem Cells using Epigenetic Molecules
por: Dhaliwal, Anandika, et al.
Publicado: (2018)

Lineage plasticity-mediated therapy resistance in prostate cancer
por: Blee, Alexandra M, et al.
Publicado: (2019)

Cell fate determination and lineage plasticity in prostate cancer
por: Gao, Dong
Publicado: (2023)

Current advances of targeting epigenetic modifications in neuroendocrine prostate cancer
por: Cheng, Wen-Chi, et al.
Publicado: (2021)

The Neuroendocrine Functions of the Parathyroid Hormone 2 Receptor
por: Dobolyi, Arpád, et al.
Publicado: (2012)

Circadian adaptations to meal timing: neuroendocrine mechanisms
por: Patton, Danica F., et al.
Publicado: (2013)

Neuroendocrine mechanisms that connect feeding behavior and stress
por: Andrews, Zane B., et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_3sebhhdm3o7lpqh99uok1k8rkr