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Serological Biomarkers of Extracellular Matrix Turnover and Neutrophil Activity Are Associated with Long-Term Use of Vedolizumab in Patients with Crohn’s Disease
Crohn’s disease (CD) is a relapsing-remitting inflammatory disease of the gastrointestinal (GI) tract characterized by increased extracellular matrix (ECM) remodeling. The introduction of the α4β7-integrin inhibitor vedolizumab (VEDO) has improved disease management, although there is a high rate of...
Autores principales: | Alexdottir, Marta S., Bourgonje, Arno R., Karsdal, Morten A., Pehrsson, Martin, Loveikyte, Roberta, van Dullemen, Hendrik M., Visschedijk, Marijn C., Festen, Eleonora A. M., Weersma, Rinse K., Faber, Klaas Nico, Dijkstra, Gerard, Mortensen, Joachim H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9329899/ https://www.ncbi.nlm.nih.gov/pubmed/35897710 http://dx.doi.org/10.3390/ijms23158137 |
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