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mTOR Modulation of I(Kr) through hERG1b-Dependent Mechanisms in Lipotoxic Heart

In the atria, the rapid delayed rectifier channel (I(Kr)) is a critical contributor to repolarization. In lipotoxic atria, increased activity of the serine/threonine mammalian target of rapamycin (mTOR) may remodel I(Kr) and predispose patients to arrhythmias. To investigate whether mTOR produced de...

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Detalles Bibliográficos
Autores principales:	Aromolaran, Kelly A., Do, Jenny, Bernardi, Joyce, Aromolaran, Ademuyiwa S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9329916/ https://www.ncbi.nlm.nih.gov/pubmed/35897638 http://dx.doi.org/10.3390/ijms23158061

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