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Spectrum of BRAF Aberrations and Its Potential Clinical Implications: Insights From Integrative Pan-Cancer Analysis

B-Raf proto-oncogene serine/threonine-protein kinase (BRAF) is frequently altered in multiple cancer types, and BRAF V600 mutations act as a prime target for precision therapy. Although emerging evidence has investigated the role of BRAF, the comprehensive profiling of BRAF expression, alteration an...

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Detalles Bibliográficos
Autores principales: Yi, Qiaoli, Peng, Jinwu, Xu, Zhijie, Liang, Qiuju, Cai, Yuan, Peng, Bi, He, Qingchun, Yan, Yuanliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9329936/
https://www.ncbi.nlm.nih.gov/pubmed/35910024
http://dx.doi.org/10.3389/fbioe.2022.806851