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Spectrum of BRAF Aberrations and Its Potential Clinical Implications: Insights From Integrative Pan-Cancer Analysis
B-Raf proto-oncogene serine/threonine-protein kinase (BRAF) is frequently altered in multiple cancer types, and BRAF V600 mutations act as a prime target for precision therapy. Although emerging evidence has investigated the role of BRAF, the comprehensive profiling of BRAF expression, alteration an...
Autores principales: | Yi, Qiaoli, Peng, Jinwu, Xu, Zhijie, Liang, Qiuju, Cai, Yuan, Peng, Bi, He, Qingchun, Yan, Yuanliang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9329936/ https://www.ncbi.nlm.nih.gov/pubmed/35910024 http://dx.doi.org/10.3389/fbioe.2022.806851 |
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