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HDAC2- and EZH2-Mediated Histone Modifications Induce PDK1 Expression through miR-148a Downregulation in Breast Cancer Progression and Adriamycin Resistance

SIMPLE SUMMARY: Epigenetic modification plays an important regulatory role in breast cancer progression. However, the relationship between epigenetic modification with tumor metabolism has not yet been fully elucidated. PDK1, as a key enzyme in glucose metabolism, mediates multiple tumors developmen...

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Detalles Bibliográficos
Autores principales:	Xie, Yunxia, Shi, Zhumei, Qian, Yingchen, Jiang, Chengfei, Liu, Wenjing, Liu, Bingjie, Jiang, Binghua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9329997/ https://www.ncbi.nlm.nih.gov/pubmed/35892859 http://dx.doi.org/10.3390/cancers14153600

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