Cargando…

Epac: A Promising Therapeutic Target for Vascular Diseases: A Review

Vascular diseases affect the circulatory system and comprise most human diseases. They cause severe symptoms and affect the quality of life of patients. Recently, since their identification, exchange proteins directly activated by cAMP (Epac) have attracted increasing scientific interest, because of...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pan, Yunfeng, Liu, Jia, Ren, Jiahui, Luo, Yun, Sun, Xiaobo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9330031/ https://www.ncbi.nlm.nih.gov/pubmed/35910387 http://dx.doi.org/10.3389/fphar.2022.929152

Ejemplares similares

Diabetic retinopathy: Involved cells, biomarkers, and treatments
por: Ren, Jiahui, et al.
Publicado: (2022)

Targeting ferroptosis as a promising therapeutic strategy to treat cardiomyopathy
por: Sun, Huiyan, et al.
Publicado: (2023)

Natural compounds targeting glycolysis as promising therapeutics for gastric cancer: A review
por: Zhao, Maoyuan, et al.
Publicado: (2022)

TRPV1: A promising therapeutic target for skin aging and inflammatory skin diseases
por: Xiao, Tengfei, et al.
Publicado: (2023)

Berberine: A Review of its Pharmacokinetics Properties and Therapeutic Potentials in Diverse Vascular Diseases
por: Ai, Xiaopeng, et al.
Publicado: (2021)

EPAC in Vascular Smooth Muscle Cells
por: Wehbe, Nadine, et al.
Publicado: (2020)

Mitochondrial Targeting Therapeutics: Promising Role of Natural Products in Non-alcoholic Fatty Liver Disease
por: Xu, Jingqi, et al.
Publicado: (2021)

NCAPG Is a Promising Therapeutic Target Across Different Tumor Types
por: Xiao, Cuicui, et al.
Publicado: (2020)

The Kappa Opioid Receptor: A Promising Therapeutic Target for Multiple Pathologies
por: Dalefield, Martin L., et al.
Publicado: (2022)

PG F(2α) Receptor: A Promising Therapeutic Target for Cardiovascular Disease
por: Zhang, Jian, et al.
Publicado: (2010)

From Rate-Limiting Enzyme to Therapeutic Target: The Promise of NAMPT in Neurodegenerative Diseases
por: Zhu, Yumeng, et al.
Publicado: (2022)

PRDM16 Regulating Adipocyte Transformation and Thermogenesis: A Promising Therapeutic Target for Obesity and Diabetes
por: Jiang, Na, et al.
Publicado: (2022)

Mitochondrial Heme Synthesis Enzymes as Therapeutic Targets in Vascular Diseases
por: Shetty, Trupti, et al.
Publicado: (2020)

EPAC1 overexpression is a prognostic marker and its inhibition shows promising therapeutic potential for gastric cancer
por: Sun, Ding-Ping, et al.
Publicado: (2017)

Targeting Tumor-Associated Antigen: A Promising CAR-T Therapeutic Strategy for Glioblastoma Treatment
por: Zhu, Guidong, et al.
Publicado: (2021)

Exchange proteins directly activated by cAMP (EPACs): Emerging therapeutic targets
por: Wang, Pingyuan, et al.
Publicado: (2017)

Natural compounds from botanical drugs targeting mTOR signaling pathway as promising therapeutics for atherosclerosis: A review
por: Wu, Qian, et al.
Publicado: (2023)

EPAC2: A new and promising protein for glioma pathogenesis and therapy
por: Richard, Seidu A.
Publicado: (2020)

CD39 and CD73 as Promising Therapeutic Targets: What Could Be the Limitations?
por: Battastini, Ana Maria Oliveira, et al.
Publicado: (2021)

Nanocurcumin: A Promising Candidate for Therapeutic Applications
por: Karthikeyan, Adhimoolam, et al.
Publicado: (2020)

Ferroptosis as a promising therapeutic strategy for melanoma
por: Ta, Na, et al.
Publicado: (2023)

Epigenetics and Vascular Senescence–Potential New Therapeutic Targets?
por: Ding, Qian, et al.
Publicado: (2020)

Monoamine Oxidase-B Inhibitor Reduction in Pro-Inflammatory Cytokines Mediated by Inhibition of cAMP-PKA/EPAC Signaling
por: Putnins, Edward E., et al.
Publicado: (2021)

Oligonucleotides—A Novel Promising Therapeutic Option for IBD
por: Scarozza, Patrizio, et al.
Publicado: (2019)

Noncoding RNAs Are Promising Therapeutic Targets for Diabetic Retinopathy: An Updated Review (2017–2022)
por: Wang, Mengchen, et al.
Publicado: (2022)

Targeting copper metabolism: a promising strategy for cancer treatment
por: Kong, Ruimin, et al.
Publicado: (2023)

Grape exosome-like nanoparticles: A potential therapeutic strategy for vascular calcification
por: Teng, Yintong, et al.
Publicado: (2022)

Exploration of 2D and 3D-QSAR analysis and docking studies for novel dihydropteridone derivatives as promising therapeutic agents targeting glioblastoma
por: Pan, Meichen, et al.
Publicado: (2023)

Ferroptosis: A new therapeutic target for bladder cancer
por: Zeng, Fan, et al.
Publicado: (2022)

Exosome derived from stem cell: A promising therapeutics for wound healing
por: Lv, Hui, et al.
Publicado: (2022)

Plant-Derived Compounds as Promising Therapeutics for Vitiligo
por: Pang, Yaobin, et al.
Publicado: (2021)

Extracellular vesicles derived from host and gut microbiota as promising nanocarriers for targeted therapy in osteoporosis and osteoarthritis
por: Cheung, Kenneth Chat Pan, et al.
Publicado: (2023)

Editorial: Vascular smooth muscle cell fate and vascular remodeling: Mechanisms, therapeutic targets, and drugs, volume I
por: Wang, Qilong, et al.
Publicado: (2022)

Targeting Calcium Homeostasis in Myocardial Ischemia/Reperfusion Injury: An Overview of Regulatory Mechanisms and Therapeutic Reagents
por: Wang, Ruiying, et al.
Publicado: (2020)

TMAO as a potential biomarker and therapeutic target for chronic kidney disease: A review
por: Zixin, Ye, et al.
Publicado: (2022)

EPAC in Nice
Publicado: (1990)

EPAC impact
Publicado: (1994)

EPAC 2004
Publicado: (2004)

EPAC 2004
Publicado: (2004)

EPAC 2004
Publicado: (2004)

Cannot write session to /tmp/vufind_sessions/sess_tv4qilro46riftvbp2qdc9ppuc