1,4-Naphthoquinone (CNN1) Induces Apoptosis through DNA Damage and Promotes Upregulation of H2AFX in Leukemia Multidrug Resistant Cell Line

The multidrug resistance (MDR) phenotype is one of the major obstacles in the treatment of chronic myeloid leukemia (CML) in advantage stages such as blast crisis. In this scenario, more patients develop resistance mechanisms during the course of the disease, making tyrosine kinase inhibitors (TKIs)...

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Detalles Bibliográficos
Autores principales: de Sousa Portilho, Adrhyann Jullyanne, da Silva, Emerson Lucena, Bezerra, Emanuel Cintra Austregésilo, Moraes Rego Gomes, Carinne Borges de Souza, Ferreira, Vitor, de Moraes, Maria Elisabete Amaral, da Rocha, David Rodrigues, Burbano, Rommel Mário Rodriguez, Moreira-Nunes, Caroline Aquino, Montenegro, Raquel Carvalho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9330061/
https://www.ncbi.nlm.nih.gov/pubmed/35897681
http://dx.doi.org/10.3390/ijms23158105

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