Cargando…

The Antidiabetic Activities of Neocryptotanshinone: Screened by Molecular Docking and Related to the Modulation of PTP1B

The aim of this study was to provide a practical experimental basis for the development of Neocryptotanshinone (NCTS) as an effective hypoglycemic drug and a theoretical method for the rapid screening of natural compounds with hypoglycemic effects. Molecular docking was used to screen the most suita...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hao, Jie, Qian, Zhiming, Liu, Zijian, Zhang, Guirong, Wang, Di, Han, Weiwei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9330310/ https://www.ncbi.nlm.nih.gov/pubmed/35893885 http://dx.doi.org/10.3390/nu14153031

Ejemplares similares

Molecular docking and virtual screening for novel protein tyrosine phosphatase 1B (PTP1B) inhibitors
por: Rao, Pasupuleti Sreenivasa, et al.
Publicado: (2012)

Neocryptotanshinone inhibits lipopolysaccharide-induced inflammation in RAW264.7 macrophages by suppression of NF-κB and iNOS signaling pathways
por: Wu, Chuanhong, et al.
Publicado: (2015)

Docking of oxalyl aryl amino benzoic acid derivatives into PTP1B
por: Verma, Neelam, et al.
Publicado: (2008)

Antiobesity and Antidiabetes Effects of a Cudrania tricuspidata Hydrophilic Extract Presenting PTP1B Inhibitory Potential
por: Kim, Dae Hoon, et al.
Publicado: (2016)

The importance of including the C-terminal domain of PTP1B(1-400) to identify potential antidiabetic inhibitors
por: Coronell-Tovar, Andrea, et al.
Publicado: (2023)

Mechanochemical Synthesis of Thiazolidinone-Triazoles Derivatives as Antidiabetic Agents: Pharmacokinetics, Molecular Docking, and In Vitro Antidiabetic Properties
por: Taj, M. B., et al.
Publicado: (2023)

Synthesis of small peptide compounds, molecular docking, and inhibitory activity evaluation against phosphatases PTP1B and SHP2
por: Kostrzewa, Tomasz, et al.
Publicado: (2018)

Pharmacokinetics and drug-likeness of antidiabetic flavonoids: Molecular docking and DFT study
por: Bitew, Mamaru, et al.
Publicado: (2021)

PTP1B inhibitor promotes endothelial cell motility by activating the DOCK180/Rac1 pathway
por: Wang, Yuan, et al.
Publicado: (2016)

In Silico Screening and Identification of Antidiabetic Inhibitors Sourced from Phytochemicals of Philippine Plants against Four Protein Targets of Diabetes (PTP1B, DPP-4, SGLT-2, and FBPase)
por: Macalalad, Mark Andrian B., et al.
Publicado: (2023)

Antidiabetic Bis-Maltolato-OxoVanadium(IV): Conversion of inactive trans- to bioactive cis-BMOV for possible binding to target PTP-1B
por: Scior, Thomas, et al.
Publicado: (2009)

Assessment of Antidiabetic Activity of the Shikonin by Allosteric Inhibition of Protein-Tyrosine Phosphatase 1B (PTP1B) Using State of Art: An In Silico and In Vitro Tactics
por: Saeed, Mohd, et al.
Publicado: (2021)

ETS proto-oncogene 1 modulates PTP1B expression to participate in high glucose-mediated endothelial inflammation: Ets1 modulates PTP1B expression to participate in inflammation
por: Jiang, Lili, et al.
Publicado: (2022)

Liraglutide Exerts Antidiabetic Effect via PTP1B and PI3K/Akt2 Signaling Pathway in Skeletal Muscle of KKAy Mice
por: Ji, Wenjun, et al.
Publicado: (2014)

Quantitative proteomics identifies PTP1B as modulator of B cell antigen receptor signaling
por: Schwarz, Jennifer J, et al.
Publicado: (2021)

Hippocampal miRNA-144 Modulates Depressive-Like Behaviors in Rats by Targeting PTP1B
por: Li, Yuhuan, et al.
Publicado: (2021)

Synthesis and Molecular Docking Studies of Novel Biheterocyclic Propanamides as Antidiabetic Agents Having Mild Cytotoxicity
por: Abbasi, Muhammad Athar, et al.
Publicado: (2023)

Deconstructing allostery by computational assessment of the binding determinants of allosteric PTP1B modulators
por: Hardie, Adele, et al.
Publicado: (2023)

Combined Experimental and Computational Study of V-Substituted Lindqvist Polyoxotungstate: Screening by Docking for Potential Antidiabetic Activity
por: Maalaoui, Ahlem, et al.
Publicado: (2023)

Molecular docking based screening analysis of GSK3B
por: Ogunleye, Adewale J, et al.
Publicado: (2019)

Molecular docking of phenolic compounds and screening of antioxidant and antidiabetic potential of Moringa oleifera ethanolic leaves extract from Qassim region, Saudi Arabia
por: Chigurupati, Sridevi, et al.
Publicado: (2022)

An expanded allosteric network in PTP1B by multitemperature crystallography, fragment screening, and covalent tethering
por: Keedy, Daniel A, et al.
Publicado: (2018)

Screening and identification of potential PTP1B allosteric inhibitors using in silico and in vitro approaches
por: Shinde, Ranajit Nivrutti, et al.
Publicado: (2018)

Prone Transpsoas Lateral Interbody Fusion (PTP LIF) with Anterior Docking: Preliminary functional and radiographic outcomes
por: NaPier, Zachary
Publicado: (2023)

In Silico Molecular Docking and In Vitro Antidiabetic Studies of Dihydropyrimido[4,5-a]acridin-2-amines
por: Bharathi, A., et al.
Publicado: (2014)

Antidiabetic, antioxidant, molecular docking and HPTLC analysis of miquelianin isolated from Euphorbia schimperi C. Presl
por: Ahmed, Sarfaraz, et al.
Publicado: (2019)

Molecular Docking and Simulation Studies of Antidiabetic Agents Devised from Hypoglycemic Polypeptide-P of Momordica charantia
por: Arif, Rawaba, et al.
Publicado: (2021)

Green Tea Catechins Induce Inhibition of PTP1B Phosphatase in Breast Cancer Cells with Potent Anti-Cancer Properties: In Vitro Assay, Molecular Docking, and Dynamics Studies
por: Kuban-Jankowska, Alicja, et al.
Publicado: (2020)

Evaluation of Antidiabetic Effect of Luteolin in STZ Induced Diabetic Rats: Molecular Docking, Molecular Dynamics, In Vitro and In Vivo Studies
por: Kahksha,, et al.
Publicado: (2023)

PTP1B triggers integrin-mediated repression of myosin activity and modulates cell contractility
por: González Wusener, Ana E., et al.
Publicado: (2015)

The PTP1B mutant PTP1B∆2–4 is a positive regulator of the JAK/STAT signalling pathway in Hodgkin lymphoma
por: Zahn, Malena, et al.
Publicado: (2020)

Dual PTP1B/TC-PTP Inhibitors: Biological Evaluation of 3-(Hydroxymethyl)cinnoline-4(1H)-Ones
por: Derkach, Kira V., et al.
Publicado: (2023)

Structure guided studies of the interaction between PTP1B and JAK
por: Morris, Rhiannon, et al.
Publicado: (2023)

Antidiabetic Potential of Volatile Cinnamon Oil: A Review and Exploration of Mechanisms Using In Silico Molecular Docking Simulations
por: Stevens, Nicole, et al.
Publicado: (2022)

Antioxidant, Enzyme Inhibitory, and Molecular Docking Approaches to the Antidiabetic Potentials of Bioactive Compounds from Persicaria hydropiper L.
por: Ayaz, Muhammad, et al.
Publicado: (2022)

Identification of potent aldose reductase inhibitors as antidiabetic (Anti-hyperglycemic) agents using QSAR based virtual Screening, molecular Docking, MD simulation and MMGBSA approaches
por: Bakal, Ravindra L., et al.
Publicado: (2022)

Ve-ptp Modulates Vascular Integrity by Promoting Adherens Junction Maturation
por: Carra, Silvia, et al.
Publicado: (2012)

PTP1B regulates Eph receptor function and trafficking
por: Nievergall, Eva, et al.
Publicado: (2010)

PTP1B regulates lymphocytes responses androgen deprivation
por: Arredouani, Simo, et al.
Publicado: (2014)

PTP1B: mediating ROS signaling to silence genes
por: Boivin, Benoit, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_2iolilnh39omekggfc3l03ebdj