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Digoxin Derivatives Sensitize a Saccharomyces cerevisiae Mutant Strain to Fluconazole by Inhibiting Pdr5p
The poor outcome of treatments for fungal infections is a consequence of the increasing incidence of resistance to antifungal agents, mainly due to the overexpression of efflux pumps. To surpass this mechanism of resistance, a substance able to inhibit these pumps could be administered in associatio...
Autores principales: | de Moraes, Daniel Clemente, Tessis, Ana Claudia, Rollin-Pinheiro, Rodrigo, Princival, Jefferson Luiz, Villar, José Augusto Ferreira Perez, Barbosa, Leandro Augusto, Barreto-Bergter, Eliana, Ferreira-Pereira, Antônio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9330353/ https://www.ncbi.nlm.nih.gov/pubmed/35893137 http://dx.doi.org/10.3390/jof8080769 |
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